Background and Objective: Rivers are a small part of the world's running water and one of the main sources of water supply for various uses, including agriculture, drinking and industry. In this study, in order to investigate the quality status of part of the water of Shavar River located in Khuzestan province using water quality indicators 4 (NSFWQI), 5 (IRWQI) and (BCWQI) 6 in the study period from Hamzeh village to Shavar dam. Material and Methodology: Sampling of 5 selected stations along the river route was performed during six periods of winter of 1994 and spring of 1995 and after transferring the samples to the laboratory, the values of quality parameters to calculate water quality indicators including: BOD5, COD, dissolved oxygen, nitrate and other qualitative parameters were determined by standard methods. Findings: According to the NSFWQI calculation results, for all stations during the sampling periods are between 40-36 and indicate poor water quality. Also, the index calculation results (IRWQI) for all stations during the sampling periods are between the values of 46-43 and indicate relatively poor water quality. For the index (BCWQI) for all stations during the sampling period is between the values of 27-39 and indicates the appropriate quality for agricultural use. Discussion and Conclusion: River water quality in all sampling periods is at a low quality level that water use is only suitable for agricultural purposes. Also, the inflow of drainage from agricultural fields containing chemical fertilizers, domestic wastewater is one of the main reasons for the decline in water quality. In determining river water quality, the index (IRWQI) is better than other indicators in Iran.