Agricultural exploitation systems in Iran's agricultural sector have always played an important role in integration and allocation of human, physical, and environmental resources. The main purpose of this study was to determine the optimal utilization system in the agricultural sector of Kohgiluyeh-va-Boyerahmad province according to the economic, social, and ecological criteria. Delphi technique was used to collect the required information and the questionnaire was completed by holding briefings with the participation of 34 provincial experts, including experts in the farming system, rural cooperative organization, managers of cooperatives, and unions and leading farmers. Analytical Hierarchy Process (AHP) and Expert Choice software were used to analyze the data. The results, showed that based on total economic, social, and ecological criteria and 18 sub-criteria, with a relative weight of 0. 293, Mosha cooperative system is ranked first and is the most suitable alternative. Furthermore, with a relative weight of 0. 143, agro-industry system is ranked fifth as the least suitable alternative. It is worth mentioning that joint farming stock, peasant, and production cooperative systems ranked second, third, and fourth, respectively. Therefore, more participation of the villagers in the production of crops and sustainable agricultural development will be achieved by employing Mosha cooperatives, joint farming stock companies, and agricultural mechanization. Taken together, employment of these exploitation systems will prevent the fragmentation of agricultural lands under the current conditions.