The aim of this study was to determine the effect of aerobic exercise with vitamin E consumption on non-alcoholic fatty liver disease in people15 to 18 years. For this purpose, 44 patients with an average age of 15.79±0.97 (years), Weight 95.10±13.08 (kg) and BMI of 31.46±3.22 (kg/m2) randomly divided into 4 groups of 11 persons (1. aerobic exercise with diet 2. Vitamin E with diet 3. Vitamin E+aerobic exercise with diet 4. Diet). Variables of Weight, body mass index, waist to hip ratio, blood sugar, cholesterol, triglycerides, low-density lipoprotein, high density lipoprotein, alanine aminotransferase, aspartate aminotransferase and elasticity of the liver was measured before and after 8 weeks intervention. The paired T-test and ANOVA showed that in comparison within groups decrease in indicators such as weight in the first, third and fourth groups, body mass index and waist-to-hip ratio in the first and third groups, triglyceride in the first and second groups, cholesterol in first and fourth groups, low-density lipoprotein in the fourth group, the second group and alanine amino transferase in second group and liver elasticity was significant in all groups (P<0.05). In comparison between groups and between variables except of high-density lipoprotein and cholesterol difference was not significant (P<0.05) that in Scheffe post hoc test results in favor of vitamin E with diet group were observed.So, it seems that aerobic exercise along with diet control or the daily intake of vitamin E (400IU) along with diet control have a significant role in the improvement or decline of nonalcoholic fatty liver disease. But to achieve the most effective way and a single treatment strategy requires further research.