Objectives: The purpose of the present study is to provide a model for the relationship between the Islamic lifestyle, wisdom and moral intelligence with a tendency towards high-risk behavior with the mediating role of psychological well-being. Method: This study is one of the descriptive-correlation schemes through structural equation modeling (SEM). The statistical population of this study is all students of Mohaghegh Ardebili University who studied in the years 2018. Using multi-stage random cluster sampling, 373 people were selected as sample. Data were gathered by Islamic Life Style test, Three Dimensional Wisdom Scale, Moral Competency Inventory, High risk Behavior scale and Ryff’ s Psychological Wellbeing Scales. Results: About Fitness indices in the structural equation model the main hypothesis, it can be said that the amount of the structural equation model is significant at the level of 5% error. Also, the ratio of χ 2 to degree of freedom in the structural equation model of the main hypothesis according to the desired criterion, indicates fit for the model. Therefore, there is a relationship between the tendency towards high-risk behaviors and Islamic lifestyle, wisdom and moral intelligence directly, also indirectly, through psychological well-being. Conclusion: The authors of the survey conclude that the mentioned model can be a good pattern for identifying the factors involved in high-risk students' behavior, and the results of this study can be used to reduce the tendency toward high-risk behavior among students.