The purpose of the present study is to investigate the effect of aerobic training on blood pressure and blood glucose in patients with hypertension and non-insulin dependent diabetes mellitus. Forty patients (Male & Female) with up to 140/90 mmHg blood pressure and 120 mg/dl glucose were studied. The subjects were randomly selected and divided in to control and experimental groups. The experimental group consisted of 20 patients (10 males and 10 females) taking part in aerobic training at 60-75% HRR max, three sessions a week and sixty minutes per Session. Then blood pressure, fasting blood glucose Test, weight and BMI were measured before and after the training. The control group, however, received no intervention. The results of this study showed that systolic blood pressure, diastolic blood pressure, blood glucose, weight and BMI decreased in the experimental group (p<0.05) the difference between the two groups in blood glucose, weight and BMI in experimental and the control group was not significant (p>0.05). However, the difference in systolic and diastolic blood pressure in males and females in the experimental and control groups was significant after the training (p<0.05). Compared to females, the difference in BMI in males was also significant for the experimental group (p<0.05), but the systolic and diastolic blood pressure, blood glucose and weight in males in the experimental group showed no meaningful difference compared to females (p>0.05). The results on the whole, showed that aerobic training for eight weeks has more effect on systolic and diastolic pressure. They decreased in the experimental group. BMI in males was also reduced more, compared to females.