Journal of Rafsanjan University of Medical Sciences
Year:2023 | Volume:22 | Issue:9|Papers Count:8

Background and Objectives: Suicide is one of the causes of death worldwide, which causes a long-term impact on the family, society, and economy. The present study investigated suicidal behavior in suicide attempters based on depression with the mediation of thwarted belongingness and perceived burdensomeness. Materials and Methods: The current study is descriptive and correlational. A total of 365 patients who attempted suicide and were hospitalized at Baharloo Hospital in Tehran in 2022 were selected through convenience sampling. Beck Depression Inventory-II (BDI-II), Interpersonal Needs Questionnaire (INQ) (thwarted belongingness and perceived burdensomeness), and the Suicidal Behaviors Questionnaire-Revised (SBQ-R) were administered to the suicide attempters. The Sobel test was used to examine mediation hypotheses, and structural equation modeling (SEM) was used to evaluate the proposed model. Results: The results showed that there were positive and significant relationships between depression score and suicidal behavior (r=0. 314, p<0. 001), thwarted belongingness and suicidal behavior (r=0. 395, p<0. 001), and perceived burdensomeness and suicidal behavior (r=0. 410, p<0. 001). The model fit indices confirmed the path of depression to suicidal behavior and depression with the mediation of thwarted belongingness and perceived burdensomeness. Conclusion: The results of this study showed that depression plays a crucial role in suicidal behavior directly and indirectly through the mediation of thwarted belongingness and perceived burdensomeness. Therefore, identification, diagnosis, and treatment of people suffering from depression and examining interpersonal needs will effectively prevent and reduce suicidal behavior.

Background and Objectives: Migraine is the second neurological disorder with deep pain that causes a wide range of problems for the affected people and those around them. Therefore, the purpose of this study was to model the causality of pain perception in migraine sufferers based on distress intolerance with the mediating role of fear of disease progression. Materials and Methods: The current research is descriptive and the statistical population included all people with migraine who referred to clinics and neurologists' offices in Mashhad in 2022,out of which, 200 applicants were selected as a sample using the convevience sampling method. And they responded to Simons and Gaher's Emotional Distress Tolerance, Melzack's Pain Perception, and Herschbach et al. ’s Fear of Disease Progression Questionnaires. To analyze the data, structural equation modeling was used. Results: A positive and significant relationship was observed between pain perception score and fear of disease progression score (r=0. 470, p<0. 01), and a negative and significant relationship was observed between pain perception score and distress tolerance score (r=-0. 425, p<0. 01). Furthermore, emotional distress tolerance had indirect association with pain perception through affecting the fear of disease progression. Conclusion: The findings showed that the fear of disease progression plays a mediating role between the intolerance of distress and the perception of pain in migraine sufferers. Considering the association of pain perception and intolerance of distress and fear of disease progression in migraine, psychologists and specialists can use the improvement of these factors to increase the effectiveness of other methods for migraine treatment.

Background and Objectives: Spermatogonial stem cells (SSCs) can generate embryonic stem-like (ES-Like) cells, both of which possess the potential for pluripotent stem cells. The gene ZBTB16 (Zinc Finger and BTB Domain Containing 16) plays various roles in signaling pathways, cellular differentiation regulation, and growth. The aim of this research was to identify signaling pathways associated with the ZBTB16 gene using bioinformatics methods and investigate the expression levels of this gene in SSCs and ES-Like cells. Materials and Methods: In this experimental study, initially, 100 genes with connections to ZBTB16 were extracted from the protein database and analyzed using relevant software. Subsequently, ES-Like cells were extracted from mouse testicular SSCs and cultured. Then, the expression of ZBTB16 in ES-Like cells and SSCs was examined through immunocytochemistry and immunohistochemistry staining. Results: The results indicated that the expression of ZBTB16 was demonstrated in the undifferentiated population of SSCs and ES-Like cells. It was found that deleting ZBTB16 from the gene network could disrupt undesirable signaling pathways since ZBTB16 is involved in enriching specific pathways as a specific transcription factor. Conclusion: The experimental findings can support the analysis of spermatogonial cell growth in both in vivo and in vitro. Bioinformatics methods, by identifying biological functions that ZBTB16 regulates, have shown that ZBTB16 can be used as a target gene to weaken certain undesirable pathways.

Background and Objectives: Domestic violence is associated with harmful health consequences and can overshadow married life. Based on this, the present study was conducted with the aim of determining the effectiveness of the educational package based on domestic violence on reducing frustration and marital instability. Materials and Methods: This was a quasi-experimental study with a pre-test and post-test design with a control group and a three-month follow-up. The statistical population included all the women involved in domestic violence who referred to counseling centers in Shiraz in 2021. Based on the purposeful sampling method, 30 people were selected and randomly replaced in the experimental group (15 people) and the control group (15 people). The measurement tool was Kayser's (1993) Marital Frustration Questionnaire and Edward et al. ’s (1987) Marital Instability Questionnaire. The experimental group received 14 sessions of 60 minutes for 7 consecutive weeks and the control group did not receive any intervention. The data were analyzed using mixed analysis of variance method. Results: The results of data analysis showed that after the intervention, the effect of the training package based on domestic violence on reducing frustration (F=580. 452, η=0. 954, p<0. 001) and marital instability (F=425. 009, η=0. 938, p<0. 001) of women was significant, and these positive effects remained stable during the follow-up period. Conclusion: The results of the current study showed that the educational package based on domestic violence is effective in reducing frustration and marital instability of women. Therefore, it is recommended to use this approach to reduce women's marital problems.

Background and Objectives: The different experience of bereavement of the survivors of the deceased infected with corona, its effect on the mental health of the survivors, and the recognition of effective psychological treatments these days is one of the important challenges in the field of health. The aim of the research was to compare the effectiveness of treatment focused on compassion and logotherapy on the life expectancy and time perspective of the families of those who died due to the corona virus. Materials and Methods: This study was a quasi-experimental type with a pretest-posttest design. The statistical population included the families of those who died due to the corona virus in Shahrekord City in 2022. The sample size was 45 people who were purposefully selected and randomly assigned into two experimental groups (15 people each) and a control group (15 people). Miller and Powers’ Life Expectancy and Zimbardo and Boyed’s Time Perspective Questionnaires were used to collect information. The experimental groups received treatment focused on Gilbert's compassion and Frankl's logotherapy in 8 sessions of 90 minutes, but the control group did not receive any intervention. Data were analyzed using multivariate analysis of covariance. Results: The results indicated that logotherapy is more effective on present-hedonic time perspective (p<0. 001) and there is no significant difference between the two mentioned treatments in life expectancy, past-negative time perspective, future time perspective, time perspective transcendence-future, positive past time perspective, and present time perspective believing in destiny (p<0. 05). Conclusion: According to the results of the research, the focused treatment of compassion and logotherapy are effective interventions to increase life expectancy and change the time perspective of the families of those who died due to the corona virus.

Background and Objectives: Hypertension is a chronic disease and studies have shown that one-third of deaths from cardiovascular diseases are related to uncontrolled blood pressure. The present study was conducted with the aim of determining the effectiveness of positive psychotherapy on systolic and diastolic blood pressure and psychological well-being of women with hypertension. Materials and Methods: The present research method was a quasi-experimental study with a pretest-posttest, and follow-up design with a control group. The statistical population included all women with hypertension who referred to Valiasr Hospital in Rasht City in 2023, and 32 qualified volunteers were selected by the purposive sampling method. Psychological Well-Being Questionnaire (Ryff, 1995) and digital brachial sphygmomanometer were the instruments employed in this research. In order to perform intervention, positive psychotherapy was implemented for the experimental group in 8 sessions,while, there was no intervention for the control group. Data were analyzed using two-way repeated measures analysis of variance (ANOVA). Results: The results showed that positive psychotherapy significantly reduced systolic and diastolic blood pressure and increased the psychological well-being of women with hypertension, so that this effectiveness had been lasting over the time (p<0. 001). Conclusion: The results of the present study showed that positive psychotherapy has been effective on systolic and diastolic blood pressure and psychological well-being of women with hypertension. Therefore, positive psychotherapy intervention can be used for solving the problems associated with patients suffering from hypertension in hospitals and private counseling centers by health professionals and nurses.