Background and Objectives: Hypogonadism is a common complication in men with type 2 diabetes. The present study aimed to determine the frequency of hypogonadism and some related factors in men with type 2 diabetes referred to the Endocrinology Clinic of Ali Ibn Abi Talib Hospital of Rafsanjan University of Medical Sciences in 2021. Materials and Methods: In this descriptive study, 111 men with type 2 diabetes were examined. After completing the questionnaire and measuring blood pressure and waist circumference, 10 cc of fasting blood was taken to measure serum levels of total testosterone (TT), follicle stimulating hormone (FSH), luteinizing hormone (LH), and glycosylated hemoglobin (HbA1c). Data was analyzed using chi-square test, independent t-test, Pearson’s correlation test, and logistic regression. Results: The mean and standard deviation of age of patients was 58. 61±10. 62 years. Twenty six patients (23. 42%) had hypogonadism. With increasing body mass index, the TT levels (p=0. 034), LH (p=0. 008) and FSH (p=0. 028) significantly decreased. With increasing HbA1c, the levels of TT (p=0. 035), LH (p=0. 004) and FSH (p=0. 001), with increasing systolic blood pressure, the level of LH (p=0. 025), and with increasing age, the levels of LH and FSH (p<0. 001) significantly increased,however, with increasing waist circumference, the levels of TT (p=0. 006), LH and FSH (p<0. 001) significantly reduced. Mean TT (p=0. 011), LH (p=0. 017), and FSH (p=0. 014) levels were significantly higher in those taking the drug. Conclusion: With an increase in waist circumference, disease duration, and follicle stimulating hormone, the odds of hypogonadism increased. It is recommended to the health officials to take the necessary preventive measures including increasing the awareness of the male community.