Background and Objective: Educating patients plays an important role in improving their quality of life. The collaborative care model is a new method of self-care training. This study was conducted to evaluate the effect of collaborative care model on the quality of life and metabolic control indexes in patients with type 2 diabetes.Materials and Methods: In this semi-experimental study, 60 patients with type 2 diabetes visiting diabetes clinic of Jiroft Hospital were studied. The participants were selected based on the convenience sampling method. To implement the collaborative model that included four stages of motivation, preparation, engagement, and evaluation, the patients were divided into four groups, and the model was executed for three months for each group. Data collection tools included a researcher-made questionnaire including demographic characteristics, metabolic indexes and vital signs and the quality of life questionnaire for patients with diabetes. The collected data were analyzed using Wilcoxon, Mac-Nemar and paired t-test in SPSS, version 20.Results: After performing the collaborative care model, the total mean quality of life increased from 50.7±5.7 to 68.3 ±5.2. The results of Wilcoxon test showed a significant difference in care and metabolic indexes (P<0.001). The quality of life improved in different dimensions compared to the pre-intervention stage (P<0.001).Conclusion: The implementation of this model improves the quality of life and metabolic indexes. Therefore, the use of collaborative care model as an effective model for educating patients with type 2 diabetes is recommended.