Following the approach of Donald Trump, US foreign policy faced an innovative orientation, especially in relation to international economics. In this context, the First American doctrine prescribes the necessity of increasing attention to Americanism against globalism; significant implications for the economy of this state; economic relations with other states, in particular China, Europe, . . ., and The world economy. In fact, his protectionist policies have created a vague prospect for international trade, which reflects on its effects and features in the agenda of this paper. The main research question is: America foreign policy orientation in the course of Trump on the basis of "priority to the interests of America" (America First) during the period 2017-2019 has been how to affect international trade? In response, the hypothesis is that: the US foreign policy over the 2017-2019 period focuses on the priority of US interests by relying on economic nationalism and the adoption of supportive trade policies, the patterns of its commercial engagement with the core actors of the global business, especially China and Europe, are tense Which has had a negative impact on the growth of international trade in the short term.