Regarding the role of the financial system as a complement to the real sector of the economy, its proper function has always been the focus of concern for economic policy makers. Given the importance of the relationship between financial stability and economic performance, this study investigates it empirically in OPEC countries by using annual data during 2000-2016. To estimate the relationship, we follow the dynamic panel Model an the mentioned model is estimated using the systemic GMM estimator after controlling the effect of countries financial deepening level. In this research, Alternative indicators of financial stability such as: institutional indicators, micro and macro indicators, and author-introduced indicators, and also, economic performance index such as: GDP per capita growth, household per capita consumption growth, and the growth of gross fixed capital formation are used. The results indicate that financial stability has a significant positive effect on economic performance in OPEC countries.