Introduction: Many studies, especially in recent years, have evaluated and controlled the occupational heat stress in Iran using environmental indices. However, so far, no comprehensive study has been conducted to review and classify these studies. Therefore, this study aimed to review and investigate the occupational studies performed by environmental heat stress indices in Iran. Material and method: In the present study, the published articles from 2000 to 2016 were searched using Persian and English keywords including heat stress, heat strain, hot condition, warm condition, occupational health, thermal environment and Iran in databases such as Web of Science, Google Scholar, PubMed, Scopus, Science Direct, SID, Magiran, Civilica, Iran Medex, Barakatkns and Irandoc. Finally, 134 articles were included in this study. Results: Based on the results, most studies have been carried out in the indoor industrial environments of Isfahan, Tehran, and Assaluyeh between years of 2010 to 2016. As well as, WBGT index with 76 percent and the UTCI and PHS indices with 0. 6 percent had the highest and lowest usage in all environments and industries, respectively. In addition, the industries of the refinery, steel, glasswork, melting and casting, mines, and ship repairs have the highest mean values of WBGT index, respectively. Conclusion: The results showed the need to more attention of researchers for conducting studies in outdoor environments, in different cities of Iran, on development and validation of novel heat stress indices, and on implementation and evaluation of control measures in the environments with high heat stress.