Introduction & Objective: Diagnostic tests are important in treatment planning and prediction of the probability of gangrene in hand crushing injuries. This study determines and compares sensitivity, specificity, Positive Predictive Value and Negative Predictive Value of six common diagnostic tests of ischemia in prediction of probability of gangrene.Materials & Methods: The study has been performed on 144 crushed fingers that at presentation based on color, temperature and capillary refill were ischemic and vascular reconstruction was impossible. Conservative treatment including minimal debridment, fracture reduction, skin closure and immobilization in splint was done and sensitivity, specificity, Positive Predictive Value, Negative Predictive Value of diagnostic tests including: color, temperature, capillary refill, pinprick with gauge needle number 23, handheld Doppler and pulse oximetry in prediction of probability of gangrene was evaluated.Results: Color, capillary refill, Doppler and pulse oximetry have the greatest sensitivity (100%) and pinprick with needle has the least sensitivity (68.75%). In contrast, pinprick test has the greatest specificity (100%) and color and temperature have the least ones (17.8%). Pinprick test has the greatest Positive Predictive Value (100%), and, color capillary refill, pulse oximetry and Doppler have the greatest negative Predictive Value (100%). Negative Predictive Value for temperature is the least one (90%).Conclusions: Color, capillary refill, pulse oximetry and Doppler because of Negative Predictive Value equal to100% are invaluable, when they are normal. In contrast, pinprick with gauge needle number 23 because of Positive Predictive Value equal to 100% is invaluable when it is normal. Temperature, because of inconclusive Negative Predictive Value and Positive Predictive Value is not very helpful in treatment planning.