Desertification refers to the process of degradation of fragile and unsustainable ecosystems, which, due to the change in use or pressure on the land, is spreading through human intervention and ultimately leads to a reduction in biological production. In some parts of the world, with the expansion of deserts, food production is reduced and water resources are dried, as a result, populations move to other areas. Due to the limited capacity of cities to provide facilities and services, these migrations will have serious socio-economic problems. In this study, the long-run and short-run relationship between desertification variables, GDP, agricultural area, forest area, average annual precipitation, investments made to deal with desertification in the form of Kuznets environmental hypothesis and using ARDL PANEL Distribution determining model for agricultural province with Iranian destructs (Tehran, Khorasan, Kerman, Yazd, Isfahan, Sistan and Baluchestan And Semnan) have been investigated. The results showed that the inverse U-shape of the Kuznets environmental hypothesis in the studied provinces was confirmed in the long run.