Journal of Neyshabur University of Medical Sciences
Year:2020 | Volume:8 | Issue:1 (26)|Papers Count:13

Introduction This study aimed to evaluate the effectiveness of the “ well-being therapy" method on the clinical syndrome in patients with major depression as a randomized clinical trial. Materials and Methods This randomized clinical trial study was performed on patients with major depression who referred to the psychological clinic of Shamim, Bojnurd city in the period from November 2018 to February 2019 years. Participants eligible to enter the study were assigned to the intervention and control groups with a random block method. In the intervention group, Well-being therapy was performed in 8 sessions of 50 minutes and once a week, and the control group did not receive any treatment. Both groups were evaluated before and after the study and two months later by the Second Depression Beck Depression Inventory (BDI-II). Data were analyzed by T-test independent and generalized estimation equations (GEE) in STATA12 statistical. Results A total of 24 subjects had inclusion criteria in which 12 participants were randomly assigned to each group. Independent T-test results showed a significant difference between the mean depression scores of the groups after the study and the follow-up period (P-value <0. 05). The results of the GEE test showed that in the well-being group, the mean depression scores decreased 10. 90 rather than the control group (p-value <0. 0001). Conclusion The results of this study showed that well-being therapy can be effective in reducing depression in patients with major depression.

The heart rate deflection point (HRDP) is the heart rate deviation point of the straight line that is defined in the study of the relationship between work and time and it is used as a criterion for the intensity of exercise planning. The purpose of the present study is to review the Methodological approach of heart rate deflection point the new methods for determining this point. In the present study, the dimensions of HRDP methodology were examined in two areas of HRDP-related physiological mechanisms and HRDP determination methods. In the section on HRDP determination methods, determining the basal heart rate, HRDP calculation, and measurement methods, as well as training protocols, were the most important dimensions of methodology in measuring this point. The present study, by examining the findings of previous research, obtained a suitable and integrated summary of the physiological mechanisms associated with HRDP and the methodological dimensions of HRDP. The results indicate that disagreement about the ability of HRDP to determine the anaerobic threshold related to the methodology of HRDP measurement. Infect, it affects the definition of the anaerobic threshold. Therefore, studies on it continue.

Introduction Glanzmann's thrombasthenia is the hereditary disease of abnormal function in the platelets. Despite being rare, this disease Given the direct relationship between the rate of cousin marriages and the disease prevalence. The main problem in the treatment of the disease is performing particularly major surgeries. In the present case report, we stated case management of the hemorrhagic ovarian cyst with a history of Gelzmen's disease. Case report With a history of Gelzmen's disease, the adolescent girl presented with a pain in the abdominal area. After performing ultrasound and taking a medical history and the related tests conducted, the patient was diagnosed with a hemorrhagic ovarian cyst. Before the surgery, the patient received three vials of the recombinant activated factor VII. During and after the operation, she was received three vials in every two hours, and three vials every six hours until homeostasis. Finally, the patient was discharged four days later with the satisfactory general condition Conclusion Concerning the previous studies as well as our experience, we could manage the patient bleeding during and after the surgery for treatment of the hemorrhagic ovarian cyst by preoperative injections of the platelets and the factor VII during and after the operation.

Introduction Breast cancer is the most common cancer among women. One of the approaches to prevent and treat various cancers is to use plant compounds. This study aimed to investigate the effect of S. setifera essential oil on the MCF-7 human breast cancer cell line and comparing it with Doxorubicin as a known anti-cancer medicine. Materials and Methods Cells are treated by 0. 01-0. 025 μ l/ml of essential oil at 24, 48, and 72 hours and cell viability and colony formation ability were quantified. Also, essential oil composition is analyzed by GC-Mass. Results The S. setifera essential oil decreased the viability and CFU of cells, significantly. EO IC50 was reported as 0. 0206, 0. 0175 and 0. 0173 μ l/ml over 24, 48 and 72 hours. In addition, the S. setifera essential oil GC-Mass analysis showed that most compounds are related to hydrocarbon alkanes and terpenoids. Conclusion Due to the S. setifera essential oil cytotoxicity efficacy of and the observation of compounds obtained from the GC-Mass test, Probably the essential oil cytotoxicity effects are related to hydrocarbon alkanes and terpenoids compounds.

Introduction Using the views of nurses and patients and their participation in decisionmaking can provide more complete information about the quality of services. The purpose of this study was to compare nurses 'and patients' viewpoints about the quality of nursing care. Materials and Methods In this descriptive-analytical study, 300 hospitalized patients and 100 nurses working in 22 Bahman Neyshabur teaching hospitals participated. Patients were selected through systematic random sampling and nurses were selected through the census. QUALPAC questionnaire was used for data collection. Descriptive statistics, Kruskal– Walli, and U-Mann-Whitney were used to analyze the collected data. Results The results of the present study show that the quality of nursing care from the viewpoint of nurses and patients is at a desirable level. Conclusion The present study shows that the quality of nursing care from the viewpoint of nurses and patients is at a desirable level.

Introduction Diabetes is the most common glandular disease in the world. The purpose of this study was to investigate the effect of six weeks of increasing endurance training with L-carnitine supplementation on Bax / Bcl-2 and oxidative stress indices in the cardiac tissue of diabetic rats. Materials and Methods In this experimental study, 45 male Wistar rats (weighing 20 ± 250 gr) were randomly divided into 6 groups: healthy control, diabetic control, sham, exercise, L carnitine, and exercise and L-carnitine. Rats were diabetic with injected 95 mg nicotinamide by intraperitoneal injection and after 15 minutes of injection, 55 mg STZ per body weight. Rats receiving El Carnitine received daily 100 mg of l-carnitine orally. The aerobic exercise program was started 5 days a week, for six days, with a gradient of zero degree, speed of 10 m and time of 10 minutes in the first week and the final week of gradient it reached 5 degree, speed of 20 m and time of 40 minutes. The variables were measured by ELISA and ASA kits and in the heart tissue. One-way ANOVA and Tukey's post hoc test were used to analyze the data using the Shapiro Wylak test. Results The results showed that increasing endurance training and L-carnitine consumption had a significant effect on GPX (P = 0. 001), MDA (P = 0. 001), and Bax / Bcl2 heart rate (P = 0. 001) in diabetic rats. Conclusion It seem The research results confirm the role of aerobic exercise and Lcarnitine in improving apoptosis and oxidative stress in type 2 diabetic rats.

Introduction Marital infidelity is considered to be one of the most important traumatic factors for couples and families, and it is also a prevalent phenomenon for family and marital therapists. The present research was conducted by the aim of investigating the effectiveness of group compassion-focused counseling on internalized shame among women affected by marital infidelity. Materials and Methods The present study was a semi-experimental one that was conducted by pretestposttest and follow-up with control group design. The research population included all the women affected by marital infidelity referring to counseling centers in Gorgan, Iran, in 2019. The research sample composed of 24 women who were selected by purposeful sampling method and were assigned into experiment and control groups by random assignment method (12 subjects per group). The data gathering tool was Cook’ s Internalized Shame Scale (1993). Group compassion-focused therapy was provided in 13 120-minute sessions for the experiment group. The data were analyzed by variance analysis test with repeated measures. Results The results of variance analysis with repeated measures showed that group compassion-focused counseling led to a decrease in internalized shame in the subjects of the intervention group in the posttest and follow up stages. Moreover, the therapeutic intervention exerted a positive and significant effect on the components of internalized shame (shyness, self-esteem) (p < 0. 01). Conclusion According to the confirmation of the effectiveness of the compassion-focused approach, family counselors and therapists can use this therapeutic model for reducing the traumas caused by marital infidelity.

Introduction A narcissistic personality disorder is one of the disorders that has many different manifestations in clinical and research environments that make it difficult to diagnose and treat. This study aimed to evaluate the validity and reliability of the brief version of pathological narcissism (B-PNI) in Iranian society. Materials and Methods This was a cross-sectional study and the study sample was composed of 400 university students who were selected by available sampling. After getting the author’ s agreement, the main version of Brief Pathological Narcissism Inventory was translated through a backward translation technique and the scale was used for pilot tests on 40 people. Convergent validity was calculated using the Narcissistic Personality Inventory (NPI-16). Results Confirmatory factor analysis on grandiose and vulnerable narcissism indicated the good validity of the inventory in these factors. Composite Reliability of the subscales ranged from 0. 68 to 0. 83. The Cronbach’ s alpha coefficients obtained for this scale and its subscales from 0. 63 to 0. 83. This scale showed a good test-retest reliability in 15 days (r=0. 984, p=0. 001). Grandiose subscale just has shown the convergent validity with Narcissism personality Inventory (r=0. 4, p=0. 001) and there was not a meaningful correlation with Vulnerable narcissism (r=0. 07, p= 0. 6). Conclusion The Farsi version of the Brief Pathological Narcissism Inventory has a desirable validity and reliability and could be used in clinical activities and so in psychological researches in Iran.

Introduction The electrocoagulation process is one of the most effective treatment methods among the oxidation processes due to its unique properties such as simple design and extensive application for treating industrial wastewater. To promote this process, different ways have been proposed. In this study, the electrocoagulation process was incremented by the placement of steel wool and platinum electrodes and its potential were evaluated by decolorization of crystal violet (CV) from aqueous solution. Materials and Methods The colored solution was prepared from CV powder by its dissolution in distilled water. The spectrophotometric method (600 nm) was used to determine the color content. Electrocoagulation experiments were conducted in a 1000 mL backer and at a batch method. To evaluate the kinetic studies, first and second-order models were used. Toxicity tests were also performed using coliform bacteria to ensure the reduction of crystal violet toxicity. Results The results showed that the process could remove the colored solution with a high percentage rate of about 99. 63% under optimal conditions (pH 9, time of 60 minutes, applied current 0. 4 amperes and color concentration about 200 mg/L). The microbial toxicity test also indicated that the treated wastewater in this method can be reused or discharged in the environment. Conclusion Based on the results, the electrocoagulation with steel wool-platinum electrode arrangement can be effectively used in the treatment of color containing industrial wastewater.

Introduction Soldering is one of the actions in the electronics industry processes that create disturbances in the oral, nasal, and respiratory tract. In worldwide, many people are working in this occupation. The most common to reduce employees’ exposure to chemical agents in workplaces is local exhaust ventilation. This study aims to design and install local ventilation to control exposure to soldering fumes in the electronic industry in Kerman. Materials and Methods A present Experimental study is a description-analytical that carried out in three steps in an assembly line for electronic components in Kerman in the summer of 2018: 1-collecting samples of contaminants produced during soldering 2-designing, manufacturing and installing a local exhaust ventilation 3-collecting samples of contaminants produced during soldering after designing exhaust ventilation. Lead and tin collecting samples were done based on NIOSH 7105 and NIOSH 5504 respectively. Results The results showed that employees had more exposure to the tin and lead contaminants before designing and installing local exhaust ventilation that was above the allowed rate. The results of designing exhaust ventilation of 20. 5 m3/min showed that tin and lead fumes rates could reach below the allowed rates in all workplaces. Conclusion The investigation and comparison of the allowed rates of exposure to soldering fumes and the density rates in workplaces before and after designing the local exhaust ventilation proved the high efficiency of controlling methods in the assembly line of electronic components.

Introduction Betatrophin and irisin are liver and muscle tissue produced proteins that regulate triglyceride metabolism as well as glucose homeostasis. This study was designed to evaluate the levels of betatrophin and irisin in obese rats before and after 10 weeks of aerobic training. Materials and Methods Twenty four, 8-week-old male Wistar rats (249. 8± 11. 2g) were selected and purchased for the research. After obesity induction by a high-fat diet, the animals were randomly divided into two groups: aerobic training (n = 12) and control (n = 12). Also, a matched group with normal weight was selected for baseline comparisons. The animals trained 60 min/day, 5 days/week for 10 weeks. Bodyweight, lipid and glycemic profiles, and betatrophin and irisin levels were assessed after 10 weeks of aerobic training. The data were compared using analysis of variance (P<0. 05). Results Results showed that weight mass (P<0. 01), plasma total cholesterol (P<0. 02), triglyceride (P<0. 05), and fasting glucose (P<0. 04) were reduced in obese rats following the aerobic training. Plasma betatrophin was significantly reduced in aerobic training compared to control groups (P<0. 02). Conversely, irisin concentration was significantly elevated with aerobic training (P<0. 03). Conclusion The data demonstrated that moderate-intensity aerobic training prevented obesity-induced cardiovascular disorders simultaneously with improvements in betatrophin and irisin levels in obese rats.

Introduction Malva sylvestris is a symbol of calmness and has antioxidant and radical scavenging properties. The objective of this study was to investigate the antidepressant effects of hydroalcoholic extract of Malva sylvestris leaves in mice using forced swim and tail suspension tests. Materials and Methods In this experimental study, 42 male mice were distributed in 6 groups (n=7), including vehicle (normal saline), negative control (reserpine), fluoxetine (positive control), and three groups treated with hydroalcoholic extract of Malva sylvestris (150, 300 or 450 mg/kg, i. p. ). Forced swim and tail suspension behavioral tests were used to measure depression in mice. Antioxidant capacity and malondialdehyde (MDA) content in brain of mice were determined. Results Reserpine treatment significantly increased the time of immobility in behavioral tests. Fluoxetine and extract in all three doses in the Forced swim (P<0. 001) and at 300 (P<0. 01) and 450 mg/kg (P<0. 001) doses reduced the immobility time. Reserpine significantly increased the MDA level and decreased the antioxidant capacity of brain. Fluoxetine and extract at 300 and 450 mg/kg doses increased antioxidant capacity and reduced the MDA level of brain. Conclusion The results of this study suggest that Malva sylvestris leaves have an antidepressant-like activity similar to fluoxetine which may be mediated by its antioxidant and radical scavenging components.