Effect of 10 weeks moderate aerobic training on betatrophin and irisin levels in obese Wistar rats Title

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SAREMI ABBAS; PARASTESH MOHAMMAD

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Journal: JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES Year:2020 | Volume:8 | Issue:1 (26) Page(s): 115-126

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Title

Effect of 10 weeks moderate aerobic training on betatrophin and irisin levels in obese Wistar rats Title

Author(s)

SAREMI ABBAS | PARASTESH MOHAMMAD | Issue Writer Certificate

Keywords

Aerobic exerciseQ1

betatrophinQ1

metabolic syndromeQ1

irisinQ1

Abstract

Introduction betatrophin and irisin are liver and muscle tissue produced proteins that regulate triglyceride metabolism as well as glucose homeostasis. This study was designed to evaluate the levels of betatrophin and irisin in obese rats before and after 10 weeks of aerobic training. Materials and Methods Twenty four, 8-week-old male Wistar rats (249. 8± 11. 2g) were selected and purchased for the research. After obesity induction by a high-fat diet, the animals were randomly divided into two groups: aerobic training (n = 12) and control (n = 12). Also, a matched group with normal weight was selected for baseline comparisons. The animals trained 60 min/day, 5 days/week for 10 weeks. Bodyweight, lipid and glycemic profiles, and betatrophin and irisin levels were assessed after 10 weeks of aerobic training. The data were compared using analysis of variance (P<0. 05). Results Results showed that weight mass (P<0. 01), plasma total cholesterol (P<0. 02), triglyceride (P<0. 05), and fasting glucose (P<0. 04) were reduced in obese rats following the aerobic training. Plasma betatrophin was significantly reduced in aerobic training compared to control groups (P<0. 02). Conversely, irisin concentration was significantly elevated with aerobic training (P<0. 03). Conclusion The data demonstrated that moderate-intensity aerobic training prevented obesity-induced cardiovascular disorders simultaneously with improvements in betatrophin and irisin levels in obese rats.

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APA: Copy

SAREMI, ABBAS, & PARASTESH, MOHAMMAD. (2020). Effect of 10 weeks moderate aerobic training on betatrophin and irisin levels in obese Wistar rats Title. JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES, 8(1 (26) ), 115-126. SID. https://sid.ir/paper/415668/en

Vancouver: Copy

SAREMI ABBAS, PARASTESH MOHAMMAD. Effect of 10 weeks moderate aerobic training on betatrophin and irisin levels in obese Wistar rats Title. JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;8(1 (26) ):115-126. Available from: https://sid.ir/paper/415668/en

IEEE: Copy

ABBAS SAREMI, and MOHAMMAD PARASTESH, “Effect of 10 weeks moderate aerobic training on betatrophin and irisin levels in obese Wistar rats Title,” JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES, vol. 8, no. 1 (26) , pp. 115–126, 2020, [Online]. Available: https://sid.ir/paper/415668/en

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