In this study, based on the latest Input-Output matrix of the Iranian Statistics Center, first by using the ISM method, the interaction of the industry sectors has analyzed and The ISM total effect matrix used to provide the best results. The highest level of interaction is between the construction of motor vehicles, trailers, and semi-trailers, the manufacture of coke, petroleum refining products, and nuclear fuel, and the construction of basic metals. The highest net effect is observed in the sectors of “ coke production, oil refining, and nuclear fuel production” , “ manufacturing of basic metals” and “ wood and wood products” . In the next step, the total effect matrix has been used as interpretive-interpretive modeling data to extract the MICMAC analysis chart. The results of the MICMAC analysis chart indicate that 8 sectors of the Iranian industries are autonomous, one sector is dependent, 11 sectors linkage, and two sectors are independent.