Introduction: Different studies have shown the adverse effects of anesthetic agents effect on operating rooms personnel fertility, is a challenge in anesthes-iology and obstetrics. This study was carried out to determine pregnancy complications among hospital operating rooms personnel in Khoozestan province – Iran.Materials and methods: In this case control study, we got 250 women working in operating rooms of governmental Khoozestan province hospital as case group and 250 women working in internal, pediatrics and obstetrics wards as control group. Pregnancy complications including infertility, preterm labor, fetal death, abortion, low birth weight, fetal anomaly, neonatal death were obtained using questionnaire. Data were analyzed using SPSS-16 software and chi-square test.Results: Incidence of abortion was 18.7 in case group and 9.1% in control group respectively, infertility was 14.3% in case group and 3.6% in control group, this difference was significant (p<0.05, p<0.001) but preterm birth, LBW, congenital anomaly, fetal death and ectopic pregnancy difference was not statistically significant.Conclusion: This study showed that the incidence of some pregnancy complications is similar between case and control groups but some other complication such as abortion and infertility is higher in operating room personnel than those of other wards.