Armaghane Danesh
Year:2013 | Volume:5 | Issue:5 (77)|Papers Count:11

Background & aim: Diabetes mellitus (DM) has destructive tissue effects via inducing oxidative stress. The aim of this study was to evaluate the Angi Pars effects on the expression of some CXC group of streptozotocin-induced diabetic rats.Methods: This experimental study was conducted on 48 male rats. Induced diabetic rats were done by 50 mg/ kg of Streptozotocin.56 days after induction of diabetes, rats were randomly divided into 4 groups including control, untreated diabetic, insulin-treated diabetic and diabetic treated with insulin and Angipars.24 h after the last injection the animals were bled and the expression of cxc Chemokines groups were measured by western blotting. Data were analyzed by t test.Results: Showed that CXCL10 was reduced in the treatment group and the treatment group receiving insulin in combination with angi - pars decreased significantly (P<0.05). The total concentration of CXCL12 chemokine showed that the concentration of the different groups did not change compared to the control group (P<0.05). The study showed that CXCL1 levels in the group receiving insulin in combination with angipars the chemokine concentration was significantly lower than the control group (P<0.05).Conclusion: Since, Angi-Pars consists of two major phenolic compound groups, 7 - hydroxy coumarin and flavonoids, has antioxidant, and controls the inflammatory effects of chemokine increase and balances between chemokines its effectiveness in angiogenesis can be maintain.

Background & aim: Access to the collecting system is the first step in percutaneous interventions such as cutaneous nephrolithotomy (PCNL) and endopyelotomy. Usually "using air or contrast medium injected into the pelvis and Colle 'system which is obtained under fluoroscopic guidance.The purpose of this study was to compare the efficacy and adverse effects of air Pylogram with contrast in the PCNL procedure.Methods: In this clinical trial, 100 patients older than 18 years old with renal or upper ureteral stones and upper ureter since undergoing PCNL were randomly divided into two groups. In all patients undergoing spinal anesthesia, ureteral catheter F5 was placed in supine position and the patient was returned to the prone position. The control group was injected with15-40 ml of contrast material through the catheter to represent the pelvis and Colle under fluoroscopic guidance, the intervention group were injected with 40-15 ml of room air in a similar way. Then the standard PCNL procedures were performed in all patients. Demographic characteristics and intraoperative and postoperative variables such as access time to system, radiation, hypoxia, and cardiovascular and pulmonary complications in the two groups were compared. The data included descriptive statistics, frequency, mean, standard deviation were analyzed by Student's t-test.Results: The results showed the the age, sex and mean stone size were similar in both groups.Access time control systems in control group was 7.96±1.62 minutes and in the intervention group was 7.34±1.44 minutes (P=0.049) respectivly. In control group the radiation time was 1.06±0.30 min, and in the intervention group was 0.95±0.24 min (P=0.048). Hypoxia, pulmonary and cardiovascular complications has no seen in two groups.Conclusions: [n order to represent of the pelvis and Colle in 'PCNL, the use of room air is feasible, safe and effective, time and duration of radiation have less access to the system and does not charge and can be a good alternative for Pylogram.

Background and aim: Post-traumatic stress disorder is considered as set of symptoms developed afterward an individual witness, hear or involved. The current research was purposed to compare the efficacy of eye movement desensitization and reprocessing therapy with prolonged exposure therapy on the trauma impact symptoms in veterans suffering from chronic PTSD.Methods: in this clinical trail research randomly sampled 48 veterans diagnosed with PTSD who had psychiatric records in Salman City Hospital of Yasuj. The subjects devoted in three equal groups: two experimental and one control groups. As intervention procedures the two experimental groups were exposed to eye movement desensitization and reprocessing therapy (5 sessions) and prolonged exposure therapy (10 sessions) respectively. The control group received none.Subsequent to the treatment period the triple groups were post-tested by the prior pre test scales.The data were analyzed by implementing univariate analysis of covariance (ANCOVA) and Bonferroni post hoc test.Results: Both treatment procedures significantly reduced the trauma impact symptoms (p£0.001).The results also indicated that prolonged exposure therapy was more effective concerning the trauma impact symptoms improvement.Conclusion: Intervention treatment procedures such as eye movement desensitization, reprocessing therapy, and prolonged exposure therapy sustain sufficient efficacy in trauma impact symptoms improvement while prolonged exposure therapy exceeded significantly.

Background & aim: Considering the fact that infertility causes infertility problems in the marital relationship, so, this study was aimed to determine the effectiveness of short-term couples therapy self-regulation on marital intimacy of infertile.Methods: In this clinical trial study, 20 couples were selected for sampling then they randomly into two experimental and control groups and each group was assigned 10 couples. Marital Intimacy scale was used to collect the data. Experimental intervention (self-regulatory couple therapy) was conducted on the experimental group for 8 sessions in duration of 90 minute per week. One month after completion of the training program, both groups were post-tested. Repeated measure was used to analyze the data.Results: The results showed that infertile couples marital intimacy increased self treatment groups compared with the control group (p<0.001).Conclusion: Short-term couple's therapy self-regulation is effective for increasing marital intimacy.

Background & aim: Among the various subtypes of avian influenza viruses, an H5N1 subtype virus with high pathogenicity is of great importance. The aim of this study was to determine the Phylogenetic analysis of neuraminidase gene of avian influenza virus subtype of the H5N1 in Iran in 1390.Methods: In this experimental study, two swab samples from chickens with suspected symptoms of avian influenza were tested by the World Health Organization recommendation. The neuraminidase gene of positive samples was amplified by RT-PCR technique. After sequencing the phylogenetic studies were analyzed using MEGA5 and Megalign.Results: Phylogenetic analysis showed that the virus belongs to the Clade 2.3.2.1 which is highly similar to the viruses that are identified in Mongolia in 2010. Also in the stem of this virus neuraminidase protein a number of 20 amino acid has been deleted at position 69-49.Conclusion: Due to findings of this study, it seems that the virus has entered by migratory wild birds with the origin of Mongolia.

Background & aim: Nowadays, toxic compounds derived from plants used against microbes and cancer cells. The aim of this study was to evaluate cytotoxicity of Dorema aucheri, Achillea millefollium and Artemisia aucheri using brine shrimp, Artemia urmiana, lethality test.Methods: In this experimental study, the plants were collected from the Kohgiluyeh and Boyer- Ahmad Province, then identified by a botanist. Clean and air-dried aerial parts of plants were extracted with suitable solvents. Cytotoxicity evaluation was performed using larvae hatched cysts were purchased from Urmia. Live larvae were exposed to different concentrations of extract and the numbers of live and dead larvae were counted after 24 hours. Mean of LC50 of any extracts from control and exposed live larvae were examined. The data were analyzed using the Finney's Probit analysis.Results: Hydro ethanol and chloroform extracts of Achillea millefolium, Dorema aucheri and Artemisia aucheri exhibited potent brine shrimp lethality with LC50 67.8±0.53mg.ml-1, 76.50±0.60mg.ml-1, 92.70±6.05mg.ml-1 respectively. The degree of lethality was found to be directly proportional to the concentration of extracts.Conclusion: According to BSLT, LC50 of D. aucheri, A. millefolium and A. aucheri, they were considered as toxic. So these plants could be a source of new compounds with biological activity.

Background & aim: According to the hypothesis that leishmania parasites can be escaped from immune system covered by blood group antigens (ABO) to prevent its recognition by the immune system. The aim of this study was to show the associated blood groups with symptomatic or asymptomatic visceral leishmaniasis due to Leishmania infantum in human.Methods: In this cross-sectional study the population was divided into two groups. The first group included 54 patients with kala-azar (antibody against Leishmania titers³1: 3200 by TDA with clinical specificity) and the second group consisted of 45 subjects infected with Leishmania infantum (Leishmania antibody titers of 1: 800 and 1: 1600 by DAT method and non-specific symptoms). The distribution of the 4 main blood groups ABO type, sex, age, presence or absence of symptoms, clinical signs, and response to Glucantim therapy and DAT results were evaluated. Data were analyzed by chi-square test.Results: Most of the patients in group 1 were blood group A (37%) and the lowest number of blood group were B (12.8%). In the second group, most of the ABO blood group A (42.2%) and lowest in the ABO blood group AB (8.9%).There was no significant association between blood groups and clinical symptoms (p>0.05).Conclusion: This study showed that there is no association between blood group and incidence of symptomatic and asymptomatic kala-azar.

Background & aim: Awareness about the different aspects of health during puberty plays an important role in the health of girls and finally on their health future pregnancy. The aim of the present study was to to compare the effect of role playing and classical training methods in the the improvement of puberty health among secondary school girls in Yasouj City, Iran.Methods: In this study, the educational need during puberty school girls in the interview was determined. The two schools girls were randomly selected (students any school-60). Next, a knowledge and attitude questionnaire and a behavior checklist related to the main puberty health problems were completed. Then one of the schools randomly was selected as educational interventions schools and other were studied as controls. After grouping the students into four groups of 15, intervention were conducted in four sessions including: role-play, question and answer, and lecture. In the control group, all number of school students received training on puberty health through a classical education (lectures). The results were subsequently compared. Data were analyzed by Student t-test, paired t-test, and analysis of variance.Results: The results of this study showed that the level of knowledge, attitude and behavior related to health matters during puberty showed significant improvement in the girls before and after implementation of educational intervention through role play (p<0.05).Thus, the mean score in group role play before intervention was 2.35±1.53 and after was 3.96±1.27, The mean performance score before intervention 6.04±2.34 and after was, 8.61±1.55, respectively, while in classical group differences were not statistically significant (p<0.05) Conclusion: In comparison with the classical method of health education, teaching through role play significantly improved the level of knowledge, attitude and practice related to puberty health among adolescent girls.