CYTOTOXICITY OF DOREMA AUCHRI, ACHILLEA MILLEFOLIUM AND ARTEMISIA AUCHERI BY ARTEMIA URMIANA BRINE SHRIMP LETHALITY TEST (BSLT)

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GHAVAMIZADEH M.; MOHAMMADI J.; MIRZAEI A.; SADEGH H.; AKBARTABAR M.

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Journal: Armaghane Danesh Year:2013 | Volume:5 | Issue:5 (77) Page(s): 389-399

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Information Journal Paper

Title

CYTOTOXICITY OF DOREMA AUCHRI, ACHILLEA MILLEFOLIUM AND ARTEMISIA AUCHERI BY ARTEMIA URMIANA BRINE SHRIMP LETHALITY TEST (BSLT)

Author(s)

Keywords

ARTEMIA URMIANAQ2

DOREMA AUCHRIQ3

ACHILLEA MILLEFOLIUMQ2

ARTEMISIA AUCHERIQ2

CYTOTOXICITYQ2

Abstract

Background & aim: Nowadays, toxic compounds derived from plants used against microbes and cancer cells. The aim of this study was to evaluate CYTOTOXICITY of Dorema aucheri, Achillea millefollium and ARTEMISIA AUCHERI using brine shrimp, ARTEMIA URMIANA, lethality test.Methods: In this experimental study, the plants were collected from the Kohgiluyeh and Boyer- Ahmad Province, then identified by a botanist. Clean and air-dried aerial parts of plants were extracted with suitable solvents. CYTOTOXICITY evaluation was performed using larvae hatched cysts were purchased from Urmia. Live larvae were exposed to different concentrations of extract and the numbers of live and dead larvae were counted after 24 hours. Mean of LC50 of any extracts from control and exposed live larvae were examined. The data were analyzed using the Finney's Probit analysis.Results: Hydro ethanol and chloroform extracts of ACHILLEA MILLEFOLIUM, Dorema aucheri and ARTEMISIA AUCHERI exhibited potent brine shrimp lethality with LC50 67.8±0.53mg.ml-1, 76.50±0.60mg.ml-1, 92.70±6.05mg.ml-1 respectively. The degree of lethality was found to be directly proportional to the concentration of extracts.Conclusion: According to BSLT, LC50 of D. aucheri, A. millefolium and A. aucheri, they were considered as toxic. So these plants could be a source of new compounds with biological activity.

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APA: Copy

GHAVAMIZADEH, M., MOHAMMADI, J., MIRZAEI, A., SADEGH, H., & AKBARTABAR, M.. (2013). CYTOTOXICITY OF DOREMA AUCHRI, ACHILLEA MILLEFOLIUM AND ARTEMISIA AUCHERI BY ARTEMIA URMIANA BRINE SHRIMP LETHALITY TEST (BSLT). ARMAGHAN DANESH, 5(5 (77)), 389-399. SID. https://sid.ir/paper/77921/en

Vancouver: Copy

GHAVAMIZADEH M., MOHAMMADI J., MIRZAEI A., SADEGH H., AKBARTABAR M.. CYTOTOXICITY OF DOREMA AUCHRI, ACHILLEA MILLEFOLIUM AND ARTEMISIA AUCHERI BY ARTEMIA URMIANA BRINE SHRIMP LETHALITY TEST (BSLT). ARMAGHAN DANESH[Internet]. 2013;5(5 (77)):389-399. Available from: https://sid.ir/paper/77921/en

IEEE: Copy

M. GHAVAMIZADEH, J. MOHAMMADI, A. MIRZAEI, H. SADEGH, and M. AKBARTABAR, “CYTOTOXICITY OF DOREMA AUCHRI, ACHILLEA MILLEFOLIUM AND ARTEMISIA AUCHERI BY ARTEMIA URMIANA BRINE SHRIMP LETHALITY TEST (BSLT),” ARMAGHAN DANESH, vol. 5, no. 5 (77), pp. 389–399, 2013, [Online]. Available: https://sid.ir/paper/77921/en

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