Yafteh
Year:2006 | Volume:7 | Issue:3-4 (26)|Papers Count:24

Background: The limited availability of donor sites for nerve grafting has continued to stimulate research toward finding suitable alternatives for autograft. The aim of this research was to study the effect of piezoelectric channel and collagen gel on nerve regeneration. Materials and methods: This research is an experimental study. Forty eight male rats (200-250 gr) were used. After axotomy, 1 cm segment of the sciatic nerve in rats was resected, and the gap was then bridged by one of the four methods (Polyvinylidene fluoride or PVDF + Collagen gel, Autograft, Sham and Control). All animals were evaluated at 7, 21, 35, 46, 60 and 90 days after operation by sensory test, sciatic functional index (SFI) and at 90 days by electrophysiologic testing. Sciatic nerve was studied by light and electron microscope after 4 and 12 weeks of implantation.Findings: At 90 days after operation, there was no difference in sensory testing between groups. The mean SFI at the 9 weeks, in autograft group was superior to that of Collagen gel + PVDF group (P<0.01). Mean motor nerve conduction velocity in the difference between experimental groups was not significant (P=0.05). After 4 weeks of implantation, regenerated tissue cables into PVDF tube were round shaped and the mean number of myelinated axons in Autograft group was superior to that of Collagen gel + PVDF group (P<0.001). Mean number of myelinated axons in Collagen gel + PVDF group were lower than autograft group (P<0.01), after 12 weeks of implantation.Conclusion: The positive effects of collagen gel on regeneration of nerve through a PVDF channel seen in this study suggest that it may by useful for treating peripheral nerve injuries.

Background: Vasectomy is a safe and effective method to prevent fertility. This method is practical in most regions, because it does not require complex technology. In spite of this, in some regions of Iran, It has not been approved because of the general believe that vasectomy causes impotence.Materials and Methods: In this cross-sectional research, 110 persons who were underwent vasectomy in Khorram Abad during 1999- 2002 time period were studied. Variable parameters including libido, impotence, granuloma, ejaculation problems, joint pain, sleep disorder, chronic pain, surgery regret and surgical failure were considered. The required data were collected by questionnaire and physical exam. Findings: After necessary evaluation of the cases, it was found that 60% of individuals had not any libido variation and 30% had increased libido, 85.5% of them did not have impotence, 85.5% of them did not have granuloma, 90.9% of them did not have joint pain, 89.1% of them did not have ejaculation problems, 90% of them did not have mood disorder, 95.5% of them did not have sleep disorder and 80% of them did not have chronic pain in the site of surgery. 97.3% of them did not regret of vasectomy. Surgical failure was not seen in any cases. Conclusion: It was found that vasectomy is an effective and successful method to prevent fertility. In most cases it has not side effects such as libido reduction, impotence, granuloma formation, etc. A few cases of side effects may be due to other factors. For better evaluation of long-term effects of vasectomy, a case- control study is necessary.

Background: Since ranitidine inhibits the activity of testis Na+-K+ATPase, Ca++ ATPase and Mg++ATPase enzymes, and affects estrogen metabolism in the liver and causes gynecomastia, the effects of long term use of ranitidine on testis were studied. Materials and Methods: In this experimental study 40 two-month aged male rats were divided into four groups (control group and 1, 2 & 3 test groups). Test groups were treated with 10, 70 & 400 mg/kg/day ranitidine orally for two months. Right testis of each rat excised and fixed in Buins fluid. After processing and sectioning, samples stained by H & E, PAS & Trichrom staining methods and then studied qualitatively and quantitatively. Quantitative values were assessed by Tukey test in P<0.05 with SPSS Ver.12. Findings: Ranitidine didn’t make histological lesions in testis and had no significant effect on diameter of seminiferous tubule (St) and epithelial thickness in optimal dose (10 mg/kg/day). High doses of ranitidine (70 & 400 mg/kg/day) led to cleft formation in St epithelium, ST epithelial cavitation, St atrophy and decreased St epithelial thickness, but didn’t change St diameter. Conclusion: long term consumption of Ranitidine at optimal dose didn’t cause lesions in normal testis structure and didn’t show significant effects on St diameter and thickness of St epithelium.

Background: Intravenous thrombolytic therapy is still the most common treatment for acute myocardial infarction (AMI) in our country. In recent years, some cases of suboptimal results of the treatment with a special trademark (Heberkinase) have been reported. So, we decided to evaluate the patency rate of arteries involved in infarction after treatment with Heberkinase.Materials and Methods: A total number of 110 patients admitted with AMI who received Heberkinase during the first 12 hours from beginning of symptoms and undergone Selective Coronary Angiography (SCA) during the first 20 days were enrolled in the study. TIMI flow of grade 2 or 3 and stenosis of less than 95% in the infarct-related arteries were considered as patent arteries. The findings were compared with Ejection Fraction (EF), risk factors and demographic data of the patients and also were compared with the results of previous studies.Findings: 49% of patients received Heberkinase in the first two hours, 39% between 2- 6 hours and 19% between 6 and 12 hours after beginning of symptoms. SCA was performed in 73 patients in the first 10 days and in 37 patients between days 11 to 20 (mean =8.4±4.6 days). Mean patency rate of infarct- related artery was 55%. Patency rate had no correlation with location of AMI and the infarct- related artery. EF was significantly higher in patients with patent arteries (47% versus 42%, p=0.03).Conclusion: The patency rate in our patients was about 15% less than the results reported by other investigators. The patency rate with Heberkinase was similar to the spontaneous patency rates reported in pre- thrombolytic era studies.

Background: Leishmaniasis is an infection caused by a protozoan of the genus Leishmania. This descriptive and cross- sectional study was done in order to determine the seroepidemiology of visceral leishmaniasis in East Myankooh area, in Lorestan Province during 2004– 2005 time period.Materials and methods: This study was a descriptive, cross- sectional study. Multi stage sampling was performed from all children (<12 years old) and 10% 0f adults of this geographic region. Altogether, 530 blood samples were collected to detect antileishmania antibodies. The samples were tested by serological procedures including direct agglutination test (DAT). Antibody titers of 1:3200 and more were regarded as positive and 1:1600 titer was regarded as suspected. Findings: Six cases (1.26%) were serologically positive and 1 case (0.21%) was suspicious. The titer of antiserum in 6 cases (1.13%) was 1:800. Conclusion: Seropositive cases were seen in Latvan (n=1), Darsafeh (n=2) and Bungo (n=2) villages and in tribes (n=1). There were no cases of visceral leishmaniasis in other villages. This study indicated that visceral leishmaniasis is sporadic in East Myankooh. More complete epidemiological studies are necessary for determining vectors and other probable reservoirs in this region.

Background: Succinylcholine is the most anesthetic drug used to muscle relaxation in emergency endotracheal intubation. Unfortunately it can have serious side effects. The perpose of our study was to comparison of Atracurium + Alfentanyl with succycholine.Materials and Methods: In this clinical trial study, one hundred patient randomly designated two group succinylcholine (control group) & Atracurium + Alfentanyl (experimental) after injecting of thiopental as a Alternative Method for R.S.I we can assess the difference between this two groups, with regarding to condition of intubations such as jaw relaxation, vocal cord movement and bucking.Findings: Results showed that 38% of patient had mild bucking in Atr + Alf group but all patients in succylin group were not seen (p<0.0001). Vocal cord movements was seen in expelinental group but there wasn’t in control group. Conclusion: According to results, use of Atra + Alfen method can replace the standard method (succinylcholine) for contraindicated condition. Mild vocal cord movement and mild bucking in the Atracurium + Alfentanyl can be control by that a increase in Atracurium dose.

Background: AIDS is a serious problem which affects all aspects of an individual’s life. Affected persons have a fear of being excommunicated or being abandoned by their family or friends, so they hide their infectious status. This factor causes the infection to spread more easily. Family has a major supportive role for individuals suffering from AIDS and the family support results in promotion of their life quality. Therefore, decreases the spread of the infection.Materials and Methods: This cross- sectional study was carried out on all persons infected with HIV in Khorram Abad (147 cases). Infection status of these patients have been approved before May, 2004 and their families aware of their disease. Data gathering tool was a two- part questionnaire including 36 questions, of which 16 questions concerned demographic information and the second part had 20 questions about the rate of family social support, based on standard questionnaire of PSS- F. All questionnaires were filled out at patients’ house.Findings: A majority of subjects (56.5%) benefited weak family social support. In addition, family social support from married persons was higher than single ones significantly (P=0.01). Rate of condom use in matrimony relations among married patients with more family social support was more frequent. This difference was also significant (P=0.04). Patients with higher social support were more aware of the risk of transferring the infection (P=0.05) and felt more responsibility to prevent the transfer of infection and notify their problem to others (P=0.000). Conclusion: Patients who receive more family social support, are more willing to say about their problem to other peoples, and use condom more frequently than other patients in their sexual activities. Since the majority of the studied patients received weak social support, it is recommended to improve and promote their social support by informing and educating their families.

Background: German chamomile (Matricaria recotita) as a medicinal plant has several therapeutic effects. Since the extract of this plant contains a high amount of α- bisabolol (Terpenoid), its antibacterial properties can be considered. Staphylococcus aureus as a pathogenic bacterium is important in clinical situations and food hygiene. So, investigation of effects of antibacterial compounds against this bacterium is important. Catalase as decomposing enzyme of hydrogen peroxide has important roles in physiology, identification and pathogenesis of many bacteria such as S. aureus. We evaluated the effect of sub-inhibitory concentrations of German chamomile alcoholic extract on the activity of S. aureus catalase.Materials and methods: German chamomile was prepared from the Agricultural Research Center of Tehran. Extraction was performed by ethanol 85°. Minimum inhibitory concentration and minimum bactericidal concentration of the extract against the standard strain of S. aureus was determined by tube dilution method in broth media. Effect of sub- inhibitory concentrations of the extract on catalase activity of the given bacteria was determined by titration method using KMnO4.Findings: The extract showed growth inhibitory effect at dilution of 1/32 and at dilution of 1/16 showed bactericidal effect on standard strain. Dilutions of 1/64 and 1/128 as sub- inhibitory concentrations, decreased catalase activity prominently. Conclusion: Significant decrease of catalase activity at sub- inhibitory concentrations of this extract shows that this extract affects the production of catalase at different levels such as transcription, translation or transport and etc. Therefore, it is necessary to further study this extract. This enzyme can be a new target for production of novel antimicrobial agents.

Background: Pre-eclampsia along with bleeding and infection constitute a triad that is a major cause of maternal mortality. Many factors have been recognized which can help us to determine the severity of the disease and early diagnosis of it. Since throphoblastic disorder is one of the etiological causes of pre- eclampsia, we decided to measure the level of β-hCG as a marker of detecting the activity of throphoblasts in normotensive, mild and sever pre- eclamptic pregnant women.Materials and Methods: This research was a cross- sectional study which carried out on 75 pregnant women admitted to Asali hospital. All patients matched for age and gravidity. Patients were divided into 3 groups: 25 cases of mild pre- eclampsia, 25 cases of severe pre- eclampsia and 25 cases of normotensive pregnant women. The level of β-hCG in each group was measured by ELISA assay.Findings: The level of β-hCG was 18572 ± 2123 IU/L in normotensive group; 23962±6558 IU/L in mild pre- eclamptic group and 59220±4634 IU/L in sever preeclamptic group. Statistical analysis by Kruskal- Wallis test showed that the level of β-hCG in severe pre- eclamptic group was significantly higher than the other two groups (p<0/001).The level of the hormone was not significantly different in mild preeclamptic and normotensive. Conclusion: The level of in pregnant women with severe pre- eclampsia was more than the other two groups (Normotensive and mild pre- eclamptic).Therefore, higher levels of β-hCG can determine the severity of pre- eclampsia but is not valid marker for early detection of the disease.

Background: Metabolic disturbances and dyslipidemia are among the most important medical problems in human society. Their effects on the mortality of coronary heart disease (CHD) have lead to many investigations about them.Materials and Methods: An epidemiologic cross- sectional study was carried out on 10136 persons selected randomly in Tehran urban district 13 with a minimum age of 20 years and over. We measured fasting blood sugar, blood sugar 2 hours post 75 grams oral glucose, triglyceride, total cholesterol, LDL cholesterol, HDL cholesterol, alkaline phosphatase and TSH. Degree of physical activity was registered according to "LRC" classification and anthropometric data, Social condition, family history and smoking exactly delineated. Our patients were divided into two groups. Those who had normal lipid profile and those with dyslipidemia. The latter group was further divided into two subgroups. Primary (without any risk factor for dyslipidemia) and secondary (having one or more risk factors such as DM …), ANOVA, t test, and logistic were used to analyze the level of significance. A P value of 0.05 was adopted.Findings: of all patients, 9632 cases (5619 female and 4013 male) had all detailed data needed for analysis and drawing Conclusions. 3697 female (65.8%) and 2903 male (72.3%) had as little as one type of dyslipidemia and the total prevalence was (68.5%). In female group, 1179 cases (34.8%) and in male group, 1165 cases (42.8%) had no risk factor for dyslipidemia (Primary dyslipidemia). There were 13 patients with renal failure. 100% of them were dyslipidemic. Total cholesterol, LDL.C and triglyceride increased and HDL.C in CRF group were lower (p<0.05) than non- CRF group. Conclusion: Tehran eastern population suffers from a high prevalence of dyslipidemia and a large number of persons suffer from secondary dyslipidemia. Renal failure is one of the leading causes of dyslipidemia in our society.

Background: Gastrointestinal Cancers are one of the most important causes of mortality of patients in the world as well as in our country. The North of Iran is in Asian belt of esophagus cancer, in addition, in other areas of our country gastric cancer is the most common GI Cancer. Because GI Cancers are common in Lorestan, we decided to study them in patients undergo endoscopy and colonoscopy in Shahid Rahimi hospital.Materials and Methods: This descriptive, cross- sectional research was carried out on patients from the city of Khorram Abad and its suburbs who underwent endoscopy and colonoscopy at Rahimi hospital since Sep 1996 to Sep 1999. Biopsy samples were taken from all patients and analyzed pathologically. The distributions of cancers were determined according to age, sex, type and site of cancer. Findings: Totally, 408 patients out of 3088 patients had GI cancer. The most common site of GI cancer was esophagus (52.93%). Gastric cancer had a lower frequency (37.3%) and colorectal cancer had the lowest frequency (9.57%). The frequency of all GI cancers in men was higher than women. Squamous cell carcinoma (SCC) was the most common esophageal cancer and adenocarcinoma was the most common type of cancer of stomach and colon. Conclusion: Cancers of esophagus, stomach and colon are the most frequent type of GI cancers in studied patients, respectively. Esophagus cancer had the highest frequency and colon cancer had the lowest frequency.

Background: Hyperbilirubinemia is a common problem in neonates. It is observed during the first week of the life in approximately 60% of term and 80% of preterm neonates. Kernicterus is a rare but serious consequence of undiagnosed hyperbilirubinemia. In this situation, indirect bilirubin deposit in the brain and causes transient dysfunction and occasionally permanent neuronal damage. The aim of this study was to evaluate the causes of jaundice in neonates in Madani hospital of Khorram Abad.Materials and Methods: This cross sectional study was carried out on all of the neonates who suffered from non- physiologic jaundice in Shahid Madani hospital in 2004. The method of sampling was simple. The studied variables included sex, age, positive family history, breast feeding, maternal diabetes and the age of jaundice emergence. Phototherapy or blood exchange was done based on the age, bilirubin level and gestational age. The data collected by questionnaire.Findings: Among 123- studied neonates, 72.3% were male and 28% were female. 39.9% had early jaundice which is caused by inadequate breast- feeding. 21.1% had ABO incompatibility; 2.4% Rh incompatibility and 9% G6PD deficiency. 16.3% had sepsis, 1.6% had urinary tract infection and 5.7% had asphyxia. 76.4% were treated by phototherapy and 23.4% by exchange transfusion. 2.4% of neonate had kernicterus before the time of admitting to the hospital. Conclusion: The most common cause of jaundice in the studied group was early breast feeding. So, mothers should be trained on breast feeding and its effect on reducing the neonatal jaundice.

Background: Mental health is one of the most important factors in aptitude growth of university students. Many Studies suggest that students have some types of emotional disorders. The purpose of this study is to compare mental health of Lorestan University students in relation to some academic and personal variables. Materials and Methods: This study was a descriptive research. The sample consisted of 436 university students who were selected randomly by the group sampling method. A questionnaire consisted mental health scale (MHS) as well as demographical characteristics employed for gathering required data. We used independent t- test to compare mean scores of mental health.Findings: mental health score of students with an average of 164.19 (a little more than questionnaire average 150) shows that there is a mild degree of mental health disorders in a number of students. Male students were healthier than females. There was no relationship between native and non- native students in relation to their mental health. Finally, students who were active in the university groups were healthier than who were not active in the university groups. Conclusion: In general, it can be said that Lorestan University Students have not a high degree of mental health. Furthermore, the female students are more susceptible than males and there is a meaningful relationship between mental health of students and group activities.

Background: Displaced fractures of radius and ulna bones in adults are usually treated with open reduction and internal fixation. The purpose of this research was to access functional outcome of these fractures.Materials and Methods: In this research 52 Patients who underwent ORIF with DCP 3.5 in past 5 years were investigated. Post- operation protocol was one week immobilization and then active elbow and forearm motion and then muscle strengthening after 2 months. The patients were followed for 18 months and were assessed clinically for forearm and wrist ROM & grip strength & functionally with DASH questionnaire.Findings: Pronation of the affected forearm by comparison with supination of unaffected forearm was reduced. Wrist and elbow flexion and extension were the same. Grip strength was reduced compared with unaffected limb. DASH questionnaire demonstrated high patient satisfaction.Conclusion: Anatomic reduction and internal fixation is the standard method for treatment of fractures by displacing radios and ulna in adults. According to results, it seems more intension to motions specially pronation and muscle strengthening foream after surgery will have affect on improving patients’ function specially pronation and Grip strength.

Background: Nurses have a major role in continued care and health promotion. Thus, their productivity is very important. Although many factors affect productivity, but evaluating the personnel's perception about it has a pivotal role in productivity improvement. Moreover, evaluation is a factor that can facilitate or impede productivity. Materials and Methods: This study was done in qualitative mode. Purposive sampling and open interviews were done to gather data. Content analysis approach with constant comparative analysis was used to analysis data.Findings: Nurses consider productivity both quantitatively (efficiency) and qualitatively (effectiveness). But most of them think about productivity from qualitative view. They consider the effective care which they provide to patients. One of the factors facilitating or impeding productivity is evaluation. Effective evaluation can increase productivity, and current barriers impede nursing team productivity from their viewpoint.Conclusion: Effective evaluation can improve productivity. Thus, it is suggested that current evaluation process be revised extensively.

Background: The branches of right and left subclavian arteries are important in conducting of blood to spinal cord, posterior cranial fossa, base of the neck, thyroid gland, wall of the thorax and abdomen. The routine use of internal thoracic artery as a conduit in coronary artery bypass grafting surgery requires appreciation of the anatomical variations of these vessels. So far, there is not any report about the variation of subclavian artery and it’s branches in Iran, for this reason this study have been done to see the variations of the subclavian arteries and its branches.Materials and methods: The base of the neck of 40 male cadavers approximately 40- 80 years old were dissected bilaterally with appropriate equipments. The specimens were fixed with routine fixative in dissection hall.Findings: In all specimens the left subclavian artery had normal origin but the right subclavian artery in one case originated from the beginning of the arch of aorta and in another one a retroesophageal right subclavian artery was present. We have seen that, the left vertebral artery in 2 cadavers and right vertebral artery in 1 specimen, rose from arch of aorta. This study showed that the variation of thyrocervical and internal thoracic arteries are uncommon. Conclusion: For preserving the integrity of important structures in the base of the neck, especially thyroid gland in surgery, this vascular variations are presented to physicians to keep in mind that such variations exists during diagnostic investigation and surgical procedures of the neck. An awareness of these variations is important, because this area in used for diagnostic and surgical procedures.

Background: Febrile convulsion is one of the most common types of seizure in childhood (9 month to 5 years of age). Its pathogenesis is unknown, so studying its causes is valuable. The purpose of this study was to determine the serum level of magnesium in children with FC (9 months to 5 years of age).Materials and Methods: In this analytical study, serum level of magnesium in 102 children with febrile convulsion in Shahid Madani hospital of Khorram Abad was determined. The control group was composed of 102 febrile children with no seizure. All of the children in both groups were 9 months to 5 years of age. The children in the case group had a history of episodes of documented febrile convulsion in the past years and had no underlying disease or infection in other parts of their body. In contrast, control group included febrile children with no history of episodes of documented seizure. Serum level of magnesium was determined by biochemical methods in all of the children in both groups. Finally, the data were analyzed by Chisquare and T tests.Findings: In both groups (case and control), 57% were male and 43% were female. The mean serum level of magnesium in case group, was lower than the mean serum level of magnesium in control group (P<0.0001). There was a relationship between serum level of magnesium and presence of febrile convulsion in children (P<0.0001). There was no relationship between sex and serum level of magnesium in children in both groups (P>0.05).Conclusion: There is a relationship between serum level of magnesium and the presence of febrile convulsion in children. It can be said that the deficiency of magnesium may be one of causes of FC in children. So, it is suggested to use supplements of magnesium in diet of affected children.

Background: Helicobacter pylori (HP) infection is one of the most important causes of gastrointestinal diseases such as peptic ulcer. This bacterium has recently been reported to be associated with low serum vitamin B12 level. In this study we investigated the relationship between Helicobacter pylori seropositivity and the serum B12 level in women aging 15- 49 years in Khorram Abad.Materials and Methods: This cross- sectional study conducted from 2003 to 2004 on 110 healthy women aged 15-49 years. Serum samples of patients were analyzed for vitamin B12 level and anti- Helicobacter pylori antibody. Demographic data and the history of gastrointestinal diseases were recorded in a questionnaire and then were analyzed by SPSS software.Findings: There was no significant difference between mean age of HP positive and HP negative participants 76 out of 110 (72.2%) samples were HP positive. The rate of HP seropositivity was significantly higher in patients with serum vitamin B12 level less than 12 pg/ml. who had lower and moderate vitamin B12 levels (145-180 pg/ml), that is 94% vs 64.5%, P<0.013. Conclusion: High HP seropositivity rate among patients with low- normal less serum vitamin B12 levels than normal indicates that there may be an association between HP infection and serum vitamin B12 levels.

Background: Moraxella catarrhalis is Gram negative diplococci which is a member of Neisseriacae. It was considered as a harmless commensal of the upper respiratory tract. Since 1990 its pathogenecity was established and known as a common cause of respiratory infection, particularly otitis media, sinusitis and lower respiratory tract. The aim of this research was to determine the prevalence and risk factors of Moraxella catarrhalis infection.Materials and Methods: This study performed prospectively on 123 patients with lower respiratory infection, 42 patients with otitis media and 35 patients with sinusitis. Samples (sputum, middle ear fluid, and aspirate from sinuses) were cultured on microbiologic media. Moraxella catarrhalis was isolated from some of these samples and its identity was approved by catalase, superoxole, nitrate reduction, DNase, antibiogramm (disk diffusion) and nitrocefin test for β- lactamase.Findings: the bacterium was isolated from 17 cases (11 lower respiratory infection, 4 otitis media, 2 sinusitis). There was no any relation between smoking and sex with the infection of Moraxella catarrhalis, but age (more than 50) and underlying diseases especially COPD was the risk factor for infection of Moraxella catarrhalis. Isolated bacteria were sensitive to ciprofloxacine, cefixime, and erythromycin and resistant to penecilline, amoxycilline, Co-trimoxazole, and vancomycine. Among the penecilline resistant bacteria, 93 percent produced β-lactamase. Conclusion: Moraxella catarrhalis is an important pathogen in respiratory tract especially elderly with underlying COPD. In addition, Moraxella catarrhalis may be the single cause of sinusitis and otitis media. The very high incidence of antimicrobial resistat strain in our area emphasizes the need for more epidemiological studies.

Background: Mucocele of the appendix is a clinical term for a pseudocyst that is associated with mucus extravasation into the surrounding medium. This may be the result of neoplastic causes.Case Presentation: Two cases of the mucocele of the appendix at Golestan hospital of Ahwaz were found. The first case was a 70 years lady who complained of the pain in lower part of her abdomen since 1 year ago. The patient suffered from constipation. In physical examination, there was fullness in RLQ and right flank. In complementary investigation, sonography showed a cystic mass with solid component in lower pole of right kidney with the diagnosis of mesenteric and hydatic cyst. In Abdominal CT scanning, there was duplication cyst and mesenteric cyst. The Second case was a 38 years man with chief compliant of abdominal pain since 5 days ago that was localized in RLQ with anorexia. In complementary investigation there was leukocytosis (11000 cells/μl). In sonographic examination, there was a cystic mass in RLQ with the diagnosis of appendiceal abscess. The patients were underwent operation. In both cases we observed mucocele of appendix. The pathologic report was also indicative of benign mucocele of appendix. Conclusion: appendiceal malignancies are extremely rare. The two abovementioned new cases presented with abdominal cystic mass and abdominal pain. A mucocele of benign etiology is adequately treated by a simple appendectomy.