In recent years, the economy and sustainability are considered together in construction projects. One measure that can be done in this regard is partial or full replacement of construction materials by recycled waste materials. A large volume of waste materials are produced annually from construction and demolition of civil projects. On the other hand, the construction projects consume a large amount of natural resources. Replacing the virgin materials by recycled materials, while the properties is maintained or improved, is an eco-sustainable measure. In this research, the viability of using two types of recycled construction and demolition waste materials, namely glass and brick, as powder in asphalt concrete has been evaluated. The natural filler, as control, has been replaced in different percentages (25, 50, 75 and 100%), with the recycled materials, and the mixtures have been evaluated in terms of, marshal stability, flow, indirect tensile strength, moisture damage and volumetric characteristics. The results show that, the marshal stability increases, and the flow decreases by replacing the natural filler with brick powder. However, except for 100% of replacement, replacing the natural filler with glass powder, results in a higher Marshal quotient, indicating a better strength against deformation. Also, the results show that, at both25 and 40oC, the indirect tensile strength of asphalt concrete increases with increasing the replacement by brick powder. However, although the indirect tensile strength is improved at 25oC, by 25% of replacing the natural filler with the glass powder; however, at 40oC, the indirect tensile strength decreases with increasing the replacement with glass powder. The tensile strength ratio, which is an indicator for moisture damage, is increased with increasing the brick powder content, and increased until 50% of replacement with glass powder, beyond which starts to decrease. It is also found that, the brick powder does not influence the air voids in mixture, and the voids in mineral aggregates. However, the air voids content increases, and the voids in mineral aggregates decreases with increasing glass powder content.