Background: Hand injuries are common skeleton trauma and account for 28 percent of musculoskeletal injuries. They may cause life-long disabilities. They are more common in young, and are seen more in relation to industries. This, by itself, makes them more serious injuries. The type of injury and treatment approach both have a big impact on the final disability. A study on causes and patterns of injury could guide to plan proper preventive measures. Methods: As a pilot study, a cross-sectional study has done in the whole country. In a 3-months period 128 cases of industry-related hand injuries in two major hand-trauma referral centers of Tehran were studied. Questionnaires related to the instrument and factory-type causing the trauma, the type of safety guards used at work, type of injury, and type and speed of initial instituted treatment etc. were completed by six senior medical students. The injury details were confirmed and documented, and data analyzed.Results: 128 patients with industrial hand injury had an average age of 28.9 (15-77) years; all except one were male and had isolated hand injuries. A proper wound dressing had been applied only in 40.6% (52) prior to admission. The injuries were the results of compression or sharp-blade instrument traumas in 116 or 90.7% of the time. The accidents happened in morning work shifts in 82% (105) of cases, and 47.6% (61) in the middle of the work time. The injuries were fractures in 33% (43) of the cases, tendon injuries in 40% (52), amputation in 17.1% (22) and moderate crush in 20% (26). Significant crushing was seen in 70.3% (90) patients were admitted to hospitals within 6 hours from the injury. The patients had average 13.5 months experience with their jobs. Conclusions: Industrial hand injuries in our study were mainly involved males, in their morning shift jobs. They often did not have adequate safely standards at their work place. Transport took place late with improper hospital care.