مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

115
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Expression Analysis of Long Non-coding RNAs CCAT1, CCHE1, ANRIL, BANCR, and PICART1 in Lung Cancer

Author(s)

 Shafaghat Nahid | GHAFOURI FARD SOUDEH | Sotoodehnejadnematalahi Fattah | Issue Writer Certificate 

Pages

  153-165

Abstract

 Lung Cancer is the most common malignancy with the highest mortality worldwide. lncRNAs play complex roles in the initiation and progression of Lung Cancer, thereby affecting the prognosis of patients. In this study, the expression changes of CCAT1, CCHE1, ANRIL, BANCR, and PICART1 lncRNAs in tumor tissues compared to normal tissues adjacent to the tumor were investigated and their potential as biomarkers for the diagnosis and prognosis of Lung Cancer was evaluated. In order to conduct this case-control study, 30 samples of Lung Cancer tissue and 30 samples of adjacent non-cancerous tissues (ANCTs) were collected and after total RNA extraction and cDNA synthesis, the expression levels of target lncRNAs and β, 2M reference gene was measured using SYBR Green real-time PCR assay. The statistical analysis of Real-time PCR data showed no significant difference between the expression of these lncRNAs in tumor tissue and normal tissue adjacent to the tumor (P> 0. 05). Furthermore, no significant association was observed between the expression level of these lncRNAs and any of the demographic and pathological characteristics of patients (P> 0. 05). Based on the findings of this study, it can be concluded that these lncRNAs play no role in Lung Cancer in Iranian patients. However, to confirm our results, it is necessary to evaluate the expression of these lncRNAs in a larger number of samples. .

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    Shafaghat, Nahid, GHAFOURI FARD, SOUDEH, & Sotoodehnejadnematalahi, Fattah. (2021). Expression Analysis of Long Non-coding RNAs CCAT1, CCHE1, ANRIL, BANCR, and PICART1 in Lung Cancer. JOURNAL OF ANIMAL BIOLOGY, 14(1 ), 153-165. SID. https://sid.ir/paper/1001710/en

    Vancouver: Copy

    Shafaghat Nahid, GHAFOURI FARD SOUDEH, Sotoodehnejadnematalahi Fattah. Expression Analysis of Long Non-coding RNAs CCAT1, CCHE1, ANRIL, BANCR, and PICART1 in Lung Cancer. JOURNAL OF ANIMAL BIOLOGY[Internet]. 2021;14(1 ):153-165. Available from: https://sid.ir/paper/1001710/en

    IEEE: Copy

    Nahid Shafaghat, SOUDEH GHAFOURI FARD, and Fattah Sotoodehnejadnematalahi, “Expression Analysis of Long Non-coding RNAs CCAT1, CCHE1, ANRIL, BANCR, and PICART1 in Lung Cancer,” JOURNAL OF ANIMAL BIOLOGY, vol. 14, no. 1 , pp. 153–165, 2021, [Online]. Available: https://sid.ir/paper/1001710/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button