THE EFFECT OF SOLANUM MELONGENA L. HYDRO-ALCOHOLIC EXTRACT ON CHRONIC PAIN IN MALE MICE AS COMPARED WITH MORPHINE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DASHTI RAHMATABADI M.H.; ANVARI MORTEZA; REZAEI SADRABADI M.; FALAH TAFTI H.; ZANBAGH S.; YADEGARI SADEGH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS Year:2009 | Volume:25 | Issue:1 (43) Page(s): 129-138

Download Full-Text

Persian Verion

View:

1,752

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF SOLANUM MELONGENA L. HYDRO-ALCOHOLIC EXTRACT ON CHRONIC PAIN IN MALE MICE AS COMPARED WITH MORPHINE

Author(s)

Keywords

SOLANUM MELONGENA L.Q3

CHRONIC PAINQ3

FORMALIN TESTQ3

MORPHINEQ2

MICEQ2

Abstract

Nowadays, steroidal anti inflammatory and opioide analgesics are widely used to attenuate the CHRONIC PAIN. For achieving new analgesics, many investigations have been focused on understanding the antinociceptive effects of different ethnic medicinal plants. In this study, the effects of SOLANUM MELONGENA L. extract on CHRONIC PAIN is assessed and compared with MORPHINE. This study was conducted as an experimental trial on 40 male MICE, equally and randomly divided in to 8 groups. 15 minutes after intra peritoneal injection of the extract, MORPHINE or saline, 25ml of 2.5% formalin was subcutaneously injected to left hind paw of each mouse. Immediately after this injection the animals were placed under a chamber on the FORMALIN TEST observational set up. Then pain scores were ascribed to each mouse according to pain intensity expression every 15 seconds during 1 hour. Our findings showed that 1000mg/kg Solanum melongena extract was analgesic in the 1st (acute) and the 2nd (chronic) phases of FORMALIN TEST. This effect was more prominent during 20 to 40 min. after formalin injection and the pain score was significantly less than control (p=000). The analgesic effect of this eggplant dose, didn’t show any significant difference with 4mg/kg MORPHINE sulfate in this time period (P=0.146). According to our findings the hydro-alcoholic extract of Solanum melongena reduces CHRONIC PAIN produced by formalin injection.

Cites

No record.

References

Cite

APA: Copy

DASHTI RAHMATABADI, M.H., ANVARI, MORTEZA, REZAEI SADRABADI, M., FALAH TAFTI, H., ZANBAGH, S., & YADEGARI, SADEGH. (2009). THE EFFECT OF SOLANUM MELONGENA L. HYDRO-ALCOHOLIC EXTRACT ON CHRONIC PAIN IN MALE MICE AS COMPARED WITH MORPHINE. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, 25(1 (43)), 129-138. SID. https://sid.ir/paper/104695/en

Vancouver: Copy

DASHTI RAHMATABADI M.H., ANVARI MORTEZA, REZAEI SADRABADI M., FALAH TAFTI H., ZANBAGH S., YADEGARI SADEGH. THE EFFECT OF SOLANUM MELONGENA L. HYDRO-ALCOHOLIC EXTRACT ON CHRONIC PAIN IN MALE MICE AS COMPARED WITH MORPHINE. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS[Internet]. 2009;25(1 (43)):129-138. Available from: https://sid.ir/paper/104695/en

IEEE: Copy

M.H. DASHTI RAHMATABADI, MORTEZA ANVARI, M. REZAEI SADRABADI, H. FALAH TAFTI, S. ZANBAGH, and SADEGH YADEGARI, “THE EFFECT OF SOLANUM MELONGENA L. HYDRO-ALCOHOLIC EXTRACT ON CHRONIC PAIN IN MALE MICE AS COMPARED WITH MORPHINE,” IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, vol. 25, no. 1 (43), pp. 129–138, 2009, [Online]. Available: https://sid.ir/paper/104695/en

Related Journal Papers