IN VITRO FIBRINOLYTIC ACTIVITY BY POLYPHENOLIC EXTRACT OF ZATARIA MOLTIFLORA BOISS., CURCUMA DOMESTICA VALET., HERACLEUM PERSICUM DESF. EX FISCHER AND CINNAMOMUM VERUM J.PRESL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NADERI GH.; JAFARI DINANI N.; NEJABAT N.; KELARDASHT M.; JAFARIAN DEHKORDI A.; ASGARY S.; SHAMI R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS Year:2010 | Volume:25 | Issue:4 (46) Page(s): 572-580

Download Full-Text

Persian Verion

View:

1,075

Download:

Cites:

Information Journal Paper

Title

IN VITRO FIBRINOLYTIC ACTIVITY BY POLYPHENOLIC EXTRACT OF ZATARIA MOLTIFLORA BOISS., CURCUMA DOMESTICA VALET., HERACLEUM PERSICUM DESF. EX FISCHER AND CINNAMOMUM VERUM J.PRESL

Author(s)

Keywords

FIBRINOLYTICQ3

THROMBOAMBOLIAQ3

CURCUMA DOMESTICA VALET.Q3

ZATARIA MOLTIFLORA BOISS.Q2

CINNAMOMUM VERUM J.PRESLQ3

HERACLEUM PERSICUM DESF. EX FISCHERQ3

Abstract

Disturbance in haemostatic system causes abnormal clots in vessels and THROMBOAMBOLIA.Streptokinas and urokinas are used for emergency treatment of THROMBOAMBOLIA. These drugs have certain limitations which cause serious and sometimes fatal consequences. Herbal preparations are considered to be safe and without side-effects. Since in ancient times it was reported that ZATARIA MOLTIFLORA BOISS., CURCUMA DOMESTICA VALET., CINNAMOMUM VERUM J.PRESL and HERACLEUM PERSICUM DESF. EX FISCHER present anticoagulant effects. This study performed to evaluate FIBRINOLYTIC effects of these plants. To evaluate FIBRINOLYTIC effects, labeled fibrinogen with FITC and Ca2+ was added to human plasma. Polyphenolic extracts (0.05, 0.5, 5, 50mg/ml) without and with streptokinas, were added to labeled clot. Fluorescence was determined after 10, 20, 40 and 60 minutes (Ex=478, Em=510). Our findings show that extract of Zataria moltiflora, Curcuma domestica and Cinnamomum verum reveal FIBRINOLYTIC effects (P<0.05). This effects are significant and dose dependable, but Heracleum persicum had no significant FIBRINOLYTIC effect (P>0.05). FIBRINOLYTIC effects of streptokinase in presence Zataria moltiflora are increased significantly and dose dependably. This effect in presence of Curcuma domestica and Cinnamon only in 5 and 50 mg/dl are increased. Heracleum persicum does not affect FIBRINOLYTIC properties of streptokinase. The present study indicate that, Zataria moltiflora presents best FIBRINOLYTIC effect, then Curcuma domestica and Cinnamon verum respectively reveal significant FIBRINOLYTIC effect and could lysis blood clots in vitro. Consequently, we suggest that further studies to determine in vivo clot dissolving properties and active component (s) of these herbs for clot lysis are warranted.

Cites

مروری بر خواص دارویی و کاربردی دارچین

References

No record.

Cite

APA: Copy

NADERI, GH., JAFARI DINANI, N., NEJABAT, N., KELARDASHT, M., JAFARIAN DEHKORDI, A., ASGARY, S., & SHAMI, R.. (2010). IN VITRO FIBRINOLYTIC ACTIVITY BY POLYPHENOLIC EXTRACT OF ZATARIA MOLTIFLORA BOISS., CURCUMA DOMESTICA VALET., HERACLEUM PERSICUM DESF. EX FISCHER AND CINNAMOMUM VERUM J.PRESL. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, 25(4 (46)), 572-580. SID. https://sid.ir/paper/104965/en

Vancouver: Copy

NADERI GH., JAFARI DINANI N., NEJABAT N., KELARDASHT M., JAFARIAN DEHKORDI A., ASGARY S., SHAMI R.. IN VITRO FIBRINOLYTIC ACTIVITY BY POLYPHENOLIC EXTRACT OF ZATARIA MOLTIFLORA BOISS., CURCUMA DOMESTICA VALET., HERACLEUM PERSICUM DESF. EX FISCHER AND CINNAMOMUM VERUM J.PRESL. IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS[Internet]. 2010;25(4 (46)):572-580. Available from: https://sid.ir/paper/104965/en

IEEE: Copy

GH. NADERI, N. JAFARI DINANI, N. NEJABAT, M. KELARDASHT, A. JAFARIAN DEHKORDI, S. ASGARY, and R. SHAMI, “IN VITRO FIBRINOLYTIC ACTIVITY BY POLYPHENOLIC EXTRACT OF ZATARIA MOLTIFLORA BOISS., CURCUMA DOMESTICA VALET., HERACLEUM PERSICUM DESF. EX FISCHER AND CINNAMOMUM VERUM J.PRESL,” IRANIAN JOURNAL OF MEDICINAL AND AROMATIC PLANTS, vol. 25, no. 4 (46), pp. 572–580, 2010, [Online]. Available: https://sid.ir/paper/104965/en

Related Journal Papers