Synthesis and characterization of cyclometalated Pd(II) complex bearing tyrosine: Experimental and theoretical study of interaction with biomacromolecules

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Abedan zadeh Sedigheh; Khaghani Azar Mahsa; Davaeil Bagher

Educational Videos and Scientific Workshops

Scientific Information Database

ISSN: 2588-4824

Journal Paper

Paper Information

Journal: JOURNAL OF APPLIED CHEMISTRY Year:2023 | Volume:18 | Issue:68 Page(s): 217-234

Download Full-Text

Persian Verion

View:

Download:

Cites:

Information Journal Paper

Title

Synthesis and characterization of cyclometalated Pd(II) complex bearing tyrosine: Experimental and theoretical study of interaction with biomacromolecules

Author(s)

Abedan zadeh Sedigheh | Khaghani Azar Mahsa | Davaeil Bagher | Issue Writer Certificate

Keywords

PalladacycleQ4

AminoacidQ4

DNAQ4

BSAQ4

Molecular dockingQ4

Abstract

ABSTRACTConsidering the important role of bioactive ligands in designing antitumor complexes, mononuclear C^C-cyclometalated Pd (II) complex containing amino acid, tyrosine, was synthesized and identified using Fourier-transform infrared (FT-IR) and nuclear magnetic resonance (NMR) spectroscopic methods. The interaction of the synthesized mononuclear complex with the biomacromolecules, deoxyribonucleic acid (DNA) and bovine serum albumin (BSA), was studied by UV-Vis absorption and fluorescence emission. Based on the experimental studies, an intercalating mode was proposed for the interaction between the complex and DNA. The UV-Vis absorption and fluorescence emission spectroscopies indicated the high affinity of the complex for BSA binding. Molecular docking calculations revealed that the hydrophobic interactions play important roles in complex – BSA binding.

Cites

No record.

References

No record.

Cite

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops

Download

Move to top

وبگردی