Evaluation of Pharmacological Effective Concentrations of Aspirin with/without Radiotherapy on MCF-7 Breast Cancer Cell Line

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Farhad Negin; ZAREI LEILA; Jabari Nasrolah; Gholikhani Darbroud Reza

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Veterinary Surgery Year:2018 | Volume:13 | Issue:1 (28) Page(s): 7-13

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

463

Download:

108

Cites:

Information Journal Paper

Title

Evaluation of Pharmacological Effective Concentrations of Aspirin with/without Radiotherapy on MCF-7 Breast Cancer Cell Line

Author(s)

Farhad Negin | ZAREI LEILA | Jabari Nasrolah | Gholikhani Darbroud Reza | Issue Writer Certificate

Keywords

AspirinQ1

radiotherapyQ1

MCF-7 breast cancer cell lineQ1

Abstract

Objective--The aim of the present study was to evaluate pharmacological effective concentrations of Aspirin with/without radiotherapy on growth rate of MCF-7 breast cancer cell line. Design-Experimental in vitro study. Procedures-The MCF-7 breast cancer cell line was prepared commercially and cultured. The cultured cells were then separated to labelled tubes and treated for 24 hours with 1, 2, 3, 4, and 5 mg Aspirin plus 0. 1 mg doxorubicin. Cells were then exposed to radiation. Cell proliferation and survival were measured by MTT assay, following acridine orange and propidium iodide staining methods using spectrophotometry and fluorescence microscopy. Results-The findings showed that proliferation and survival of the cells treated with 5 mM Aspirin followed by radiotherapy were significantly decreased compared to them of the control group (P<0. 05). Conclusion and clinical relevance-Although anti-proliferative activity of Aspirin was lower than that of doxorubicin, it can be considered in combination therapy because of its affordability and cost-effectiveness.

Cites

No record.

References

Cite

APA: Copy

Farhad, Negin, ZAREI, LEILA, Jabari, Nasrolah, & Gholikhani Darbroud, Reza. (2018). Evaluation of Pharmacological Effective Concentrations of Aspirin with/without Radiotherapy on MCF-7 Breast Cancer Cell Line. IRANIAN JOURNAL OF VETERINARY SURGERY (IJVS), 13(1 (28) ), 7-13. SID. https://sid.ir/paper/135706/en

Vancouver: Copy

Farhad Negin, ZAREI LEILA, Jabari Nasrolah, Gholikhani Darbroud Reza. Evaluation of Pharmacological Effective Concentrations of Aspirin with/without Radiotherapy on MCF-7 Breast Cancer Cell Line. IRANIAN JOURNAL OF VETERINARY SURGERY (IJVS)[Internet]. 2018;13(1 (28) ):7-13. Available from: https://sid.ir/paper/135706/en

IEEE: Copy

Negin Farhad, LEILA ZAREI, Nasrolah Jabari, and Reza Gholikhani Darbroud, “Evaluation of Pharmacological Effective Concentrations of Aspirin with/without Radiotherapy on MCF-7 Breast Cancer Cell Line,” IRANIAN JOURNAL OF VETERINARY SURGERY (IJVS), vol. 13, no. 1 (28) , pp. 7–13, 2018, [Online]. Available: https://sid.ir/paper/135706/en

Related Journal Papers