Factors involved in the formation of platelet aggregates

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

E. Hosseini E. Hosseini; Pezeshki S.M.S.; Hosseini E.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Year:2024 | Volume:21 | Issue:3 Page(s): 245-253

Download Full-Text

Persian Verion

View:

Download:

Cites:

Information Journal Paper

Title

Factors involved in the formation of platelet aggregates

Author(s)

Hosseini E.Hosseini" target="_blank">E. Hosseini E. Hosseini | Pezeshki S.M.S. | Hosseini E. | Issue Writer Certificate

Keywords

Blood platelets

Blood Buffy Coat

Platelet-Rich plasma

Platelet Aggregation

Abstract

Background and Objectives The collection and storage of platelets is associated with several challenges, to prevent the activation of platelets on the one hand and maintain their functional capacity during blood transfusion on the other hand. Today, one of the problems of platelet concentrate is the existence of Platelet Aggregations. The suspended particles in the platelet concentrate are believed to contain platelets that accumulate during the preparation and separation. The purpose of this study was to review important variables in the formation of Platelet Aggregations. Materials and Methods In this review article, 47 articles about aggregates in platelet products were studied from the PubMed database with platelet concentrate and platelet aggregate keywords. Results In the reviewed studies, the accumulation of platelets in the platelet concentrates prepared by the Platelet-Rich plasma (PRP) method was higher than in the buffy coat and apheresis methods. Various factors such as storage temperature, time and temperature of platelet rest, pH, induced physical stimulation, type of platelet bag, presence of bacteria, and variables related to the donor were considered as factors involved in the formation of Platelet Aggregation. Conclusions It is necessary to know the important variables in the formation of Platelet Aggregations to improve the platelet product's quality and increase the platelet transfusion's effectiveness. Using the Buffy coat method, standardizing time and temperature, preventing bacterial contamination, and considering the variables related to the donor are some of the proposed solutions to reduce the possibility of Platelet Aggregation.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans