Comparative study on in vitro, physico-chemical and antibacterial properties of 58S and 68S bioactive glasses synthesized by sol-gel method

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Moghanian Amirhossein; Zohourfazeli Mohammadamin

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Advanced Processes in Materials Engineering Year:2020 | Volume:13 | Issue:4 (51) Page(s): 17-30

Download Full-Text

Persian Verion

View:

741

Download:

Cites:

Information Journal Paper

Title

Comparative study on in vitro, physico-chemical and antibacterial properties of 58S and 68S bioactive glasses synthesized by sol-gel method

Author(s)

Moghanian Amirhossein | Zohourfazeli Mohammadamin | Issue Writer Certificate

Keywords

Sol-Gel ProcesseQ1

HydroxyapatiteQ1

BioactiveglassQ2

Bacterial ActivityQ1

Mc3t3 ProliferationQ1

Abstract

The major aim of this study was to evaluate the effect of CaO content on in vitro Hydroxyapatite formation, MC3T3cells cytotoxicity and proliferation as well as antibacterial efficiency of sol-gel derived SiO2– CaO– P2O5 ternary system. For this purpose, first two grades of bioactive glass (BG); BG-58S (mol%: 60%SiO2– 36%CaO– 4%P2O5) and BG-68S (mol%: 70%SiO2– 26%CaO– 4%P2O5)) with the fixed P2O5 content were synthesized by sol-gel method. Second, the effect of CaO content in their composition on in vitro bioactivity was investigated by soaking the BG-58S and BG-68S powders in simulated body fluid (SBF) for time periods up to 14 days. The evolution of the SBF composition was monitored by inductively coupled plasma atomic emission spectrometry (ICP-AES) analyses. Additionally, Fourier transform infrared (FTIR), X-ray diffraction (XRD) and scanning electron microscopy (SEM) were performed to characterize formed Hydroxyapatite on BG's surface. On the other hand, Live/dead staining, 3-(4, 5dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) and alkaline phosphatase (ALP) activity assays were conducted respectively, as qualitatively and quantitatively assess for cell viability, proliferation and differentiations of MC3T3cells in presence of 58S and 68S BGs. Taken together, BG-58S with enhanced MC3T3 cells proliferation and ALP activity, acceptable bioactivity and significant high antibacterial effect against MRSA bacteria is suggested as a suitable candidate in order to further functionalizing for delivery of therapeutic ions and growth factors in bone tissue engineering.

Cites

No record.

References

No record.

Cite

APA: Copy

Moghanian, Amirhossein, & Zohourfazeli, Mohammadamin. (2020). Comparative study on in vitro, physico-chemical and antibacterial properties of 58S and 68S bioactive glasses synthesized by sol-gel method. ADVANCED PROCESSES IN MATERIALS, 13(4 (51) ), 17-30. SID. https://sid.ir/paper/172517/en

Vancouver: Copy

Moghanian Amirhossein, Zohourfazeli Mohammadamin. Comparative study on in vitro, physico-chemical and antibacterial properties of 58S and 68S bioactive glasses synthesized by sol-gel method. ADVANCED PROCESSES IN MATERIALS[Internet]. 2020;13(4 (51) ):17-30. Available from: https://sid.ir/paper/172517/en

IEEE: Copy

Amirhossein Moghanian, and Mohammadamin Zohourfazeli, “Comparative study on in vitro, physico-chemical and antibacterial properties of 58S and 68S bioactive glasses synthesized by sol-gel method,” ADVANCED PROCESSES IN MATERIALS, vol. 13, no. 4 (51) , pp. 17–30, 2020, [Online]. Available: https://sid.ir/paper/172517/en

Related Journal Papers