ANTIBACTERIAL EFFECT OF BIOACTIVE GLASS NANOPARTICLES PREPARED VIA SOL GEL METHOD

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NAZEMI ZAHRA; MEHDIKHANI NAHRKHALAJI MEHDI; HAGHBIN NAZARPAK MASOUMEH; STAJI HAMID

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Journal: Journal of Kermanshah University of Medical Sciences Year:2014 | Volume:18 | Issue:7 Page(s): 381-387

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Title

ANTIBACTERIAL EFFECT OF BIOACTIVE GLASS NANOPARTICLES PREPARED VIA SOL GEL METHOD

Author(s)

NAZEMI ZAHRA | MEHDIKHANI NAHRKHALAJI MEHDI | HAGHBIN NAZARPAK MASOUMEH | STAJI HAMID | Issue Writer Certificate

Keywords

ANTIBACTERIAL ACTIVITYQ1

BIOACTIVE GLASSQ2

NANOPARTICLESQ1

Abstract

Background: Infection constitutes the most important complication caused by biomaterials. BIOACTIVE GLASSes have properties such as osteoconductivity and good restorability, some of which have revealed antibacterial effects. Therefore, these biomaterials are appropriate candidates for orthopedic and dental applications. The present study was conducted to analyze the antibacterial effect of BIOACTIVE GLASS NANOPARTICLES.Methods: In this experimental study, 37S and 58S glass compositions were synthesized via sol-gel technique. Characterization techniques such as X-ray diffraction (XRD), scanning electron microscopy (SEM) and X-ray fluorescent (XRF) were used for the prepared powders. The ANTIBACTERIAL ACTIVITY of these compounds was studied using Escherichia coli as gram negative and Staphylococcus aureus as gram positive bacteria. The antibacterial effect of samples was evaluated at concentration of 25, 50 and 100 mg/ml.Results: The particle size of the samples was mainly less than 100 nm. The 37S glass showed the highest ANTIBACTERIAL ACTIVITY and the minimum bactericidal (MBC) at 25 mg/ml concentration against both bacteria. At broth concentrations below 100 mg/ml, 58S showed no ANTIBACTERIAL ACTIVITY; however, it completely eliminated Escherichia bacteria and reduced the growth of Staphylococcus aureus bacteria.Conclusion: These BIOACTIVE GLASS nanopowders can be regarded as good candidates in orthopedic application for the treatment of bone and dental defects but need supplementary and more evaluation considering their antibacterial effect on two important bacteria.

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APA: Copy

NAZEMI, ZAHRA, MEHDIKHANI NAHRKHALAJI, MEHDI, HAGHBIN NAZARPAK, MASOUMEH, & STAJI, HAMID. (2014). ANTIBACTERIAL EFFECT OF BIOACTIVE GLASS NANOPARTICLES PREPARED VIA SOL GEL METHOD. JOURNAL OF KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES (BEHBOOD), 18(7), 381-387. SID. https://sid.ir/paper/20944/en

Vancouver: Copy

NAZEMI ZAHRA, MEHDIKHANI NAHRKHALAJI MEHDI, HAGHBIN NAZARPAK MASOUMEH, STAJI HAMID. ANTIBACTERIAL EFFECT OF BIOACTIVE GLASS NANOPARTICLES PREPARED VIA SOL GEL METHOD. JOURNAL OF KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES (BEHBOOD)[Internet]. 2014;18(7):381-387. Available from: https://sid.ir/paper/20944/en

IEEE: Copy

ZAHRA NAZEMI, MEHDI MEHDIKHANI NAHRKHALAJI, MASOUMEH HAGHBIN NAZARPAK, and HAMID STAJI, “ANTIBACTERIAL EFFECT OF BIOACTIVE GLASS NANOPARTICLES PREPARED VIA SOL GEL METHOD,” JOURNAL OF KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES (BEHBOOD), vol. 18, no. 7, pp. 381–387, 2014, [Online]. Available: https://sid.ir/paper/20944/en

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