EVALUATION OF THE THERMAL PROPERTIES OF PLLA/HA AND PLLA/45S5 COMPOSITES FOR APPLICATION IN BIOABSORBABLE INTERFERENCE SCREWS

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KHORSAND GHAENI MOHAMMAD; SADEGHI AVALSHAHR ALI REZA; NOKHASTEH SAMIRA; MOLAVI AMIRMEHDI; AMINI MASHHADI HOSSEIN

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Journal: Journal of Advanced Processes in Materials Engineering Year:2018 | Volume:11 | Issue:4 (43) Page(s): 55-65

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Title

EVALUATION OF THE THERMAL PROPERTIES OF PLLA/HA AND PLLA/45S5 COMPOSITES FOR APPLICATION IN BIOABSORBABLE INTERFERENCE SCREWS

Author(s)

Keywords

ABSORBABLE SCREWQ2

ORTHOPEDIC COMPOSITESQ2

POLY(L-LACTIC ACID)Q1

HYDROXYAPATITEQ2

BIOACTIVE GLASSQ2

Abstract

Replacement of metals with bioabsorbable polymers has shown promising results for fabrication of biomedical implants. But polymers themselves have some restrictions such as inability in osteoconduction and integration with surrounding tissue, induce foreign body reactions, reducing of pH by degradation products which can results in unwanted inflammatory reactions in related place, and weak mechanical properties in compare to metallic types. In order to alleviate these problems using of polymeric composites including bioactive particles is taken into consideration. In the present work 45S5 BIOACTIVE GLASS and hydroxyl apatite (HA) ceramic particles were used for fabrication of poly(L-Lactic acid) (PLLA) composite screws. Microstructure and thermal properties of produced samples were evaluated by differential thermal analysis (DTA), thermogravimetry (TG), scanning electron microscopy (SEM) and particle size analysis (PSA). Also for evaluation of osteogenic activity of produced samples, alkaline phosphatase (ALP) and Alizarin Red Staining assays were carried out and cytotoxicity was conducted through MTT assay. In compare to PLLA screws, PLLA/HA and PLLA/45S5 composites showed more and less thermal stability respectively. The results of cell analysis assays showed no cytotoxicity and both composites revealed proper osteogenesis potentials.

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APA: Copy

KHORSAND GHAENI, MOHAMMAD, SADEGHI AVALSHAHR, ALI REZA, NOKHASTEH, SAMIRA, MOLAVI, AMIRMEHDI, & AMINI MASHHADI, HOSSEIN. (2018). EVALUATION OF THE THERMAL PROPERTIES OF PLLA/HA AND PLLA/45S5 COMPOSITES FOR APPLICATION IN BIOABSORBABLE INTERFERENCE SCREWS. ADVANCED PROCESSES IN MATERIALS, 11(4 (43) ), 55-65. SID. https://sid.ir/paper/172573/en

Vancouver: Copy

KHORSAND GHAENI MOHAMMAD, SADEGHI AVALSHAHR ALI REZA, NOKHASTEH SAMIRA, MOLAVI AMIRMEHDI, AMINI MASHHADI HOSSEIN. EVALUATION OF THE THERMAL PROPERTIES OF PLLA/HA AND PLLA/45S5 COMPOSITES FOR APPLICATION IN BIOABSORBABLE INTERFERENCE SCREWS. ADVANCED PROCESSES IN MATERIALS[Internet]. 2018;11(4 (43) ):55-65. Available from: https://sid.ir/paper/172573/en

IEEE: Copy

MOHAMMAD KHORSAND GHAENI, ALI REZA SADEGHI AVALSHAHR, SAMIRA NOKHASTEH, AMIRMEHDI MOLAVI, and HOSSEIN AMINI MASHHADI, “ EVALUATION OF THE THERMAL PROPERTIES OF PLLA/HA AND PLLA/45S5 COMPOSITES FOR APPLICATION IN BIOABSORBABLE INTERFERENCE SCREWS,” ADVANCED PROCESSES IN MATERIALS, vol. 11, no. 4 (43) , pp. 55–65, 2018, [Online]. Available: https://sid.ir/paper/172573/en

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