Effect of Selective Laser Sintering 3D Printing Variables on the Breaking Force of Printed Tablets

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Imanian M.E.; Reza Biglari F.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Modares Mechanical Engineering Year:2020 | Volume:20 | Issue:3 Page(s): 797-806

Download Full-Text

Persian Verion

View:

581

Download:

Cites:

Information Journal Paper

Title

Effect of Selective Laser Sintering 3D Printing Variables on the Breaking Force of Printed Tablets

Author(s)

Imanian M.E. | Reza Biglari F. | Issue Writer Certificate

Keywords

SLS 3D PrintingQ1

Tablet Breaking ForceQ1

Central Composite DesignQ1

Thermoplastic PolymerQ1

Abstract

In this study, a selective laser sintering 3D printer has been designed and built. 3D laser printing is one of the flexible additive manufacturing methods, which can use different powdered materials. Recently, additive manufacturing technologies have been introduced into the pharmacy, and in August 2015, they received FDA approval as the three-dimensional drug products. By using additive manufacturing in the pharmacy, controlled release, dosage tailored to the characteristics of individuals, the desired morphology of the drugs can be achieved and we move toward the personalization of the medicine. One of the important issues is to determine the properties of tablets before printing. In this paper, the effect of important variables of selective laser sintering on Tablet Breaking Force is investigated with the aid of Central Composite Design and modeling. Using the proposed modeling, the value of each variable can be determined so that the tablets are printed with the required breaking force. The cylindrical tablets with a diameter of 1. 2 cm and a height of 3. 6 mm were printed for use in the experiments. To fabricate tablets, the Thermoplastic Polymer, Kollicoat IR (75% polyvinyl alcohol and 25% polyethylene glycol copolymer), was used and 5% paracetamol (acetaminophen) was added. Also, some edible black color was added to increase the absorption of laser light. Laser feed rate, the percentage of the tablet infill density and percentage of the added color are the studied variables. According to the results obtained in the considered range, by increasing laser feed rate, Tablet Breaking Force decreases, but tablet braking force increases by increasing infill density and amount of added color.

Cites

No record.

References

No record.

Cite

APA: Copy

Imanian, M.E., & Reza Biglari, F.. (2020). Effect of Selective Laser Sintering 3D Printing Variables on the Breaking Force of Printed Tablets. MODARES MECHANICAL ENGINEERING, 20(3 ), 797-806. SID. https://sid.ir/paper/179113/en

Vancouver: Copy

Imanian M.E., Reza Biglari F.. Effect of Selective Laser Sintering 3D Printing Variables on the Breaking Force of Printed Tablets. MODARES MECHANICAL ENGINEERING[Internet]. 2020;20(3 ):797-806. Available from: https://sid.ir/paper/179113/en

IEEE: Copy

M.E. Imanian, and F. Reza Biglari, “Effect of Selective Laser Sintering 3D Printing Variables on the Breaking Force of Printed Tablets,” MODARES MECHANICAL ENGINEERING, vol. 20, no. 3 , pp. 797–806, 2020, [Online]. Available: https://sid.ir/paper/179113/en

Related Journal Papers