AN EFFICIENT SYNTHESIS OF QUIONOLINES BY β-CYANOCARBONYL COMPOUNDS VIA FRIEDLANDER REACTION USING FECL3·6H3O AS CATALYST

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SargordanArani M.; MAHDIZADEH R.; MIRZA B.

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Journal: Journal of Applied Research in Chemistry Year:2017 | Volume:10 | Issue:4 Page(s): 85-92

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Title

AN EFFICIENT SYNTHESIS OF QUIONOLINES BY β-CYANOCARBONYL COMPOUNDS VIA FRIEDLANDER REACTION USING FECL3·6H3O AS CATALYST

Author(s)

SargordanArani M. | MAHDIZADEH R. | MIRZA B. | Issue Writer Certificate

Keywords

QUINOLINEQ2

FRIEDLANDER REACTIONQ2

CONDENSATION REACTIONSQ2

CYANO CARBONYL COMPOUNDSQ2

Abstract

The utility of QUINOLINE derivatives in the areas of medicine, food, catalyst, dye, refineries, and electronics is well established. As a result, the synthesis of QUINOLINEs have been an attractive goal for an organic chemist. In this work, amino and cyano QUINOLINEs derevatives have been synthesized in an efficient method by treatment of o-aminoaryl ketones and b-cyano carbonyl compounds using FeCl3•6H2O as an available and inexpensive catalyst via FRIEDLANDER REACTION.By this approach, the related QUINOLINEs have been prepared in excellent yields and purity and well characterized. In addition, the basic contribution of the catalyst to the efficiencies and the products has been determined and discussed. Finally, the antibacterial tests on these compounds indicate considerable effects on the antibacterial properties against Staphylooccocus positive gram and Escherichia Coli bacteria.

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APA: Copy

SargordanArani, M., MAHDIZADEH, R., & MIRZA, B.. (2017). AN EFFICIENT SYNTHESIS OF QUIONOLINES BY β-CYANOCARBONYL COMPOUNDS VIA FRIEDLANDER REACTION USING FECL₃·6H₃O AS CATALYST. JOURNAL OF APPLIED RESEARCHES IN CHEMISTRY (JARC), 10(4), 85-92. SID. https://sid.ir/paper/180055/en

Vancouver: Copy

SargordanArani M., MAHDIZADEH R., MIRZA B.. AN EFFICIENT SYNTHESIS OF QUIONOLINES BY β-CYANOCARBONYL COMPOUNDS VIA FRIEDLANDER REACTION USING FECL₃·6H₃O AS CATALYST. JOURNAL OF APPLIED RESEARCHES IN CHEMISTRY (JARC)[Internet]. 2017;10(4):85-92. Available from: https://sid.ir/paper/180055/en

IEEE: Copy

M. SargordanArani, R. MAHDIZADEH, and B. MIRZA, “AN EFFICIENT SYNTHESIS OF QUIONOLINES BY β-CYANOCARBONYL COMPOUNDS VIA FRIEDLANDER REACTION USING FECL₃·6H₃O AS CATALYST,” JOURNAL OF APPLIED RESEARCHES IN CHEMISTRY (JARC), vol. 10, no. 4, pp. 85–92, 2017, [Online]. Available: https://sid.ir/paper/180055/en

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