Study of biological effects and toxicity of mercury impregnated γ-alumina nanoparticles in Hella cancer cells and stem cells

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Soheyli Arshadi N.; Mokhtarieh A.A.; ZAMANI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: Journal of Applied Research in Chemistry Year:2020 | Volume:13 | Issue:4 Page(s): 17-26

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Information Journal Paper

Title

Study of biological effects and toxicity of mercury impregnated γ-alumina nanoparticles in Hella cancer cells and stem cells

Author(s)

Soheyli Arshadi N. | Mokhtarieh A.A. | ZAMANI M. | Issue Writer Certificate

Keywords

NanoparticleQ1

AluminaQ1

MercuryQ2

ToxicityQ1

MTT testQ1

Abstract

In this article, the Mercury-impregnated γ-Alumina Nanoparticles were prepared using impregnation of γ-Alumina Nanoparticles with Mercury acetate into the solution of water/ isopropanol, followed by hydrolysis, washing, filtration, and drying at the room temperature. The structure of these Nanoparticles were studied using X-ray diffraction (XRD) pattern. The XRD pattern was used to confirm the binding between Mercury impregnated Nanoparticles and thymine organic base in the DNA of target cell. The biological effects and Toxicity of γ-Alumina and Mercury impregnated γ-Alumina Nanoparticles on the cancer cells (Hella) and bone marrow stem cells were examined using the MTT test. Based on the results, the Toxicity of the Mercury impregnated γ-Alumina Nanoparticles on Hella cancer cells was found to be higher than that of stem cells. In other words, the Mercury impregnated γ-Alumina Nanoparticles had a significant effect on removing the Hella cancer cells. It was also found that in the lower concentrations, pure γ-Alumina Nanoparticles had lower Toxicity than Mercury impregnated Alumina.

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APA: Copy

Soheyli Arshadi, N., Mokhtarieh, A.A., & ZAMANI, M.. (2020). Study of biological effects and toxicity of mercury impregnated γ-alumina nanoparticles in Hella cancer cells and stem cells. JOURNAL OF APPLIED RESEARCHES IN CHEMISTRY (JARC), 13(4 ), 17-26. SID. https://sid.ir/paper/180152/en

Vancouver: Copy

Soheyli Arshadi N., Mokhtarieh A.A., ZAMANI M.. Study of biological effects and toxicity of mercury impregnated γ-alumina nanoparticles in Hella cancer cells and stem cells. JOURNAL OF APPLIED RESEARCHES IN CHEMISTRY (JARC)[Internet]. 2020;13(4 ):17-26. Available from: https://sid.ir/paper/180152/en

IEEE: Copy

N. Soheyli Arshadi, A.A. Mokhtarieh, and M. ZAMANI, “Study of biological effects and toxicity of mercury impregnated γ-alumina nanoparticles in Hella cancer cells and stem cells,” JOURNAL OF APPLIED RESEARCHES IN CHEMISTRY (JARC), vol. 13, no. 4 , pp. 17–26, 2020, [Online]. Available: https://sid.ir/paper/180152/en

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