Synthesis of two novel chiral ionic liquids based on pyridine from alanine amino acid and evaluation of their antibacterial and antioxidant effects

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SHAHVELAYATI ASHRAF SADAT; Khalil Moghaddam Shiva; Hosseinzadeh Soudeh

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Journal: Journal of Applied Research in Chemistry Year:2019 | Volume:12 | Issue:4 Page(s): 27-35

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Title

Synthesis of two novel chiral ionic liquids based on pyridine from alanine amino acid and evaluation of their antibacterial and antioxidant effects

Author(s)

SHAHVELAYATI ASHRAF SADAT | Khalil Moghaddam Shiva | Hosseinzadeh Soudeh | Issue Writer Certificate

Keywords

Chiral ionic liquidsQ1

PyridineQ1

Antibacterial effectQ1

Antioxidant effectQ1

BiologicalQ1

Abstract

Ionic liquids are remarkable chemical compounds, which find Biological applications in addition to solvent role in many areas of modern science. Herein, we describe a simple and effective method to synthesize two kinds of novel Chiral ionic liquids based on pyridinium named 1-(4-((1-Carboxyethyl)carbamoyl)benzyl) pyridinium Chloride [CECBPy]Cl and 1-(4-(((1-Carboxyethyl)carbamothioyl)carbamoyl) benzyl) pyridinium chloride [CECTCBPy]Cl in two steps from alanine and their optical rotation properties have been measured by polarimeter instrument. These new ionic liquids were characterized by using IR, 1HNMR, 13CNMR, and MS spectroscopy. Evaluation of the Antibacterial effects of synthetic compounds were carried out by determination of minimum inhibitory concentration )MIC) using broth micro-dilution method. Antioxidant activity of samples was measured with 2, 2-diphenyl-1-picrylhydrazyl radical scavenging activity. The results showed 1-(4-(((1-Carboxyethyl)carbamothioyl) carbamoyl) benzyl) pyridinium chloride [CECTCBPy]Cl has the best Antioxidant effect.

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APA: Copy

SHAHVELAYATI, ASHRAF SADAT, Khalil Moghaddam, Shiva, & Hosseinzadeh, Soudeh. (2019). Synthesis of two novel chiral ionic liquids based on pyridine from alanine amino acid and evaluation of their antibacterial and antioxidant effects. JOURNAL OF APPLIED RESEARCHES IN CHEMISTRY (JARC), 12(4 ), 27-35. SID. https://sid.ir/paper/180222/en

Vancouver: Copy

SHAHVELAYATI ASHRAF SADAT, Khalil Moghaddam Shiva, Hosseinzadeh Soudeh. Synthesis of two novel chiral ionic liquids based on pyridine from alanine amino acid and evaluation of their antibacterial and antioxidant effects. JOURNAL OF APPLIED RESEARCHES IN CHEMISTRY (JARC)[Internet]. 2019;12(4 ):27-35. Available from: https://sid.ir/paper/180222/en

IEEE: Copy

ASHRAF SADAT SHAHVELAYATI, Shiva Khalil Moghaddam, and Soudeh Hosseinzadeh, “Synthesis of two novel chiral ionic liquids based on pyridine from alanine amino acid and evaluation of their antibacterial and antioxidant effects,” JOURNAL OF APPLIED RESEARCHES IN CHEMISTRY (JARC), vol. 12, no. 4 , pp. 27–35, 2019, [Online]. Available: https://sid.ir/paper/180222/en

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