MACROSCOPIC EVALUATION OF THE EFFECT OF PLATELET RICH FIBRIN ON SECOND INTENTION CUTANEOUS WOUND HEALING IN THE DOG

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CHANGIZI N.; KAZEMI D.

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Journal: VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ) Year:2018 | Volume:11 | Issue:4 (44) Page(s): 357-366

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Title

MACROSCOPIC EVALUATION OF THE EFFECT OF PLATELET RICH FIBRIN ON SECOND INTENTION CUTANEOUS WOUND HEALING IN THE DOG

Author(s)

CHANGIZI N. | KAZEMI D. | Issue Writer Certificate

Keywords

PLATELET RICH FIBRINQ1

WOUND CONTRACTIONQ1

EPITHELIALIZATIONQ1

WOUND HEALINGQ2

DOGQ2

Abstract

PLATELET RICH FIBRIN is a platelet concentrate which could influence WOUND HEALING due to the release of growth factors. The purpose of this study was macroscopic evaluation of the effect of topical PLATELET RICH FIBRIN on second intention cutaneous WOUND HEALING. For this purpose, 14 adult male DOGs were used. Four full thickness 2.5×2.5 cm wounds were created on the back of each animal either side of the vertebral column. The left and right side wounds were used as treatment and control respectively. Postoperatively, the percentage of WOUND CONTRACTION, EPITHELIALIZATION and WOUND HEALING were calculated on days 7, 14, 21 and 28 and the means were compared between the two groups using the independent sample t-test at 95% significance level. The results indicated that on day 28, percentage of WOUND CONTRACTION was insignificantly lower in the treatment group (44.03±6.15 vs. 49.26±10.09) while EPITHELIALIZATION was insignificantly higher (85.90±10.32 vs. 66.24±13.45) in comparison to the control group. Also the percentage of WOUND HEALING was significantly (p=0.03) higher in the treatment group compared with the control group (92.55±5.14 vs. 83.85±3.69). Overall, the results indicated that PLATELET RICH FIBRIN improves macroscopic aspects of second intention cutaneous WOUND HEALING.

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APA: Copy

CHANGIZI, N., & KAZEMI, D.. (2018). MACROSCOPIC EVALUATION OF THE EFFECT OF PLATELET RICH FIBRIN ON SECOND INTENTION CUTANEOUS WOUND HEALING IN THE DOG. VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), 11(4 (44) ), 357-366. SID. https://sid.ir/paper/183013/en

Vancouver: Copy

CHANGIZI N., KAZEMI D.. MACROSCOPIC EVALUATION OF THE EFFECT OF PLATELET RICH FIBRIN ON SECOND INTENTION CUTANEOUS WOUND HEALING IN THE DOG. VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ)[Internet]. 2018;11(4 (44) ):357-366. Available from: https://sid.ir/paper/183013/en

IEEE: Copy

N. CHANGIZI, and D. KAZEMI, “MACROSCOPIC EVALUATION OF THE EFFECT OF PLATELET RICH FIBRIN ON SECOND INTENTION CUTANEOUS WOUND HEALING IN THE DOG,” VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), vol. 11, no. 4 (44) , pp. 357–366, 2018, [Online]. Available: https://sid.ir/paper/183013/en

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