EFFECTS OF SILVER NANOPARTICLES SYNTHESIZED THROUGH CHEMICAL REDUCTION ON PLASMA SUPEROXIDE DISMUTASE AND GLUTATHIONE PEROXIDASE ENZYMES IN RAT MODEL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHAVIDEL AGHDAM E.; NARIMANI RAD M.; LOTFI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ) Year:2016 | Volume:10 | Issue:1 (37) Page(s): 69-79

Download Full-Text

Persian Verion

View:

1,809

Download:

Cites:

Information Journal Paper

Title

EFFECTS OF SILVER NANOPARTICLES SYNTHESIZED THROUGH CHEMICAL REDUCTION ON PLASMA SUPEROXIDE DISMUTASE AND GLUTATHIONE PEROXIDASE ENZYMES IN RAT MODEL

Author(s)

GHAVIDEL AGHDAM E. | NARIMANI RAD M. | LOTFI A. | Issue Writer Certificate

Keywords

ANTIOXIDANT ENZYMESQ1

OXIDATIVE STRESSQ1

CHEMICAL REDUCTION METHODQ1

SILVER NANOPARTICLESQ1

Abstract

With possibility of synthesis of SILVER NANOPARTICLES in citrate-coated form and via chemical method, the aim of this study was synthesis of SILVER NANOPARTICLES by CHEMICAL REDUCTION METHOD and investigation of the impact of nanoparticles on superoxide dismutase and glutathione peroxidase enzymes in an animal model. SILVER NANOPARTICLES were synthesized by chemical reduction with a mixture of distilled water and sodium borohydrate and adding silver nitrate and sodium citrate to the obtained solution. In vivo study was conducted using 40 adult male rats with an average weight of 100 grams. Animals were divided into four groups, as control, placebo, and treatment groups receiving silver nanoparticle solutions (100 and 200 mg/kg, respectively). The treatment groups received silver nanoparticle solutions (100 and 200 mg/kg) on the first and the seventh days of experiment intraperitoneally. Oxidative effects of injected high concentrations of SILVER NANOPARTICLES (200 mg/kg) lead to mortality in the experimental animals. Infusion of SILVER NANOPARTICLES at concentrations of 100 and 200 milligrams per kilogram of body weight decreased the activity of plasma superoxide dismutase (SOD) and glutathione peroxidase (GPx). This reduction was significantly higher (p<0.01) at the dose of 200 mg/kg. In conclusion, studies on animal models showed that the concentrations of 100 and 200 milligrams per kilogram of body weight of SILVER NANOPARTICLES synthesized by CHEMICAL REDUCTION METHOD decreases the activity of ANTIOXIDANT ENZYMES, eventually leading to mortality.

Cites

No record.

References

Cite

APA: Copy

GHAVIDEL AGHDAM, E., NARIMANI RAD, M., & LOTFI, A.. (2016). EFFECTS OF SILVER NANOPARTICLES SYNTHESIZED THROUGH CHEMICAL REDUCTION ON PLASMA SUPEROXIDE DISMUTASE AND GLUTATHIONE PEROXIDASE ENZYMES IN RAT MODEL. VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), 10(1 (37)), 69-79. SID. https://sid.ir/paper/183236/en

Vancouver: Copy

GHAVIDEL AGHDAM E., NARIMANI RAD M., LOTFI A.. EFFECTS OF SILVER NANOPARTICLES SYNTHESIZED THROUGH CHEMICAL REDUCTION ON PLASMA SUPEROXIDE DISMUTASE AND GLUTATHIONE PEROXIDASE ENZYMES IN RAT MODEL. VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ)[Internet]. 2016;10(1 (37)):69-79. Available from: https://sid.ir/paper/183236/en

IEEE: Copy

E. GHAVIDEL AGHDAM, M. NARIMANI RAD, and A. LOTFI, “EFFECTS OF SILVER NANOPARTICLES SYNTHESIZED THROUGH CHEMICAL REDUCTION ON PLASMA SUPEROXIDE DISMUTASE AND GLUTATHIONE PEROXIDASE ENZYMES IN RAT MODEL,” VETERINARY CLINICAL PATHOLOGY (VETERINARY JOURNAL TABRIZ), vol. 10, no. 1 (37), pp. 69–79, 2016, [Online]. Available: https://sid.ir/paper/183236/en

Related Journal Papers