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Information Journal Paper

Title

SYNTHESIS OF SILVER NANOPARTICLES THROUGH CHEMICAL REDUCTION AND BIOSYNTHESIS METHODS AND EVALUATION OF THEIR ANTIBACTERIAL EFFECTS

Pages

  65-74

Abstract

 Background: SILVER NANOPARTICLES have wide applications in medicine and treatment of bacterial infections due to their disinfection properties. Chemical synthesis, biosynthesis and antibacterial properties of SILVER NANOPARTICLES have been studied previously, but regarding the high costs of chemical synthesis and the increase of antibiotic-resistance phenomenon among bacteria, assessment of the biosynthesis of SILVER NANOPARTICLES and their effects on different clinical and standard bacterial strains is of great importance.Methods: SILVER NANOPARTICLES were synthesized through chemical and biosynthesis methods and their size and size distribution was assessed TRANSMISSION ELECTRON MICROSCOPE. Chemically synthesized nanoparticles were added to tubes containing TSB medium and different bacterial strains for their ANTIBACTERIAL EFFECTS and their minimum inhibitory concentration was calculated.Results: Chemically synthesized SILVER NANOPARTICLES had high monodispersity, but biosynthesized nanoparticles had higher polydispersity. Smaller SILVER NANOPARTICLES had better ANTIBACTERIAL EFFECTS on Gram-negative and Gram-positive bacteria, in such a manner that they inhibited the bacterial growth at 0.2 mM concentration, but larger nanoparticles had lesser effects.Conclusion: Biosynthesis through BACTERIAL SUPERNATANT is cost effective, but it produces polydisperse nanoparticles. SILVER NANOPARTICLES can replace antibiotics due to their suitable ANTIBACTERIAL EFFECTS, but it should be mentioned that clinical strains are more resistant than standard strains and bacterial resistance to these nanoparticles should be checked before their prescription.

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    APA: Copy

    MOHTASHAMI, MAHNAZ, SEPEHRISERESHT, SAEED, ASLI, ESMAEEL, BOROUMAND, MOHAMMAD ALI, & GHASEMI, AHMAD. (2012). SYNTHESIS OF SILVER NANOPARTICLES THROUGH CHEMICAL REDUCTION AND BIOSYNTHESIS METHODS AND EVALUATION OF THEIR ANTIBACTERIAL EFFECTS. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 19(103), 65-74. SID. https://sid.ir/paper/11156/en

    Vancouver: Copy

    MOHTASHAMI MAHNAZ, SEPEHRISERESHT SAEED, ASLI ESMAEEL, BOROUMAND MOHAMMAD ALI, GHASEMI AHMAD. SYNTHESIS OF SILVER NANOPARTICLES THROUGH CHEMICAL REDUCTION AND BIOSYNTHESIS METHODS AND EVALUATION OF THEIR ANTIBACTERIAL EFFECTS. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2012;19(103):65-74. Available from: https://sid.ir/paper/11156/en

    IEEE: Copy

    MAHNAZ MOHTASHAMI, SAEED SEPEHRISERESHT, ESMAEEL ASLI, MOHAMMAD ALI BOROUMAND, and AHMAD GHASEMI, “SYNTHESIS OF SILVER NANOPARTICLES THROUGH CHEMICAL REDUCTION AND BIOSYNTHESIS METHODS AND EVALUATION OF THEIR ANTIBACTERIAL EFFECTS,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 19, no. 103, pp. 65–74, 2012, [Online]. Available: https://sid.ir/paper/11156/en

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