EFFECT OF QUERCETIN ON UTERUS TISSUE HISTOLOGICAL CHANGES IN OVARIECTOMIZED RATS

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MOROVVATI H.; NAJAFZADEH H.; MENATIAN K.

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Journal: JOURNAL OF CELL & TISSUE Year:2013 | Volume:4 | Issue:1 Page(s): 77-83

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Title

EFFECT OF QUERCETIN ON UTERUS TISSUE HISTOLOGICAL CHANGES IN OVARIECTOMIZED RATS

Author(s)

MOROVVATI H. | NAJAFZADEH H. | MENATIAN K. | Issue Writer Certificate

Keywords

UTERUS HISTOLOGYQ2

QUERCETINQ2

OVARIECTOMYQ2

RATQ2

Abstract

Aim: OVARIECTOMY decreases epithelial thickness of endometrium, number of cells and mucosal glands and changes other layers of uterus. QUERCETIN as a flavonoid has several properties, including free radical scavenger and antioxidant. This study has considered QUERCETIN effects on uterus tissue in ovariectomized RATs.Material and Methods: In this study, 25 female Wistar RATs were divided in 5 groups (5 samples per group): control, ovariectomized, ovariectomized-treated QUERCETIN, non ovariectomized-treated QUERCETIN, and sham.15mg/kg bw/day was intraperitonellay injected for 15 days. At the end, after RAT euthanization by Ether and removing their uterus, uterus tissues were fixed in formalin saline (10%). The tissue sections were prepared and studied using light microscope after H & E staining.Results: The thickness of endometrial layer in ovariectomized RATs decreased significantly and changed to cubic cells. Cells and glands numbers were significantly decreased in comparison with control. Endometrium thickness, cell and glands numbers significantly increased in ovariectomized-treated QUERCETIN.Conclusion: The results showed that QUERCETIN can improve changes arising from OVARIECTOMY in uterus tissue as antioxidant, when ovarian hormones are absent.

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APA: Copy

MOROVVATI, H., NAJAFZADEH, H., & MENATIAN, K.. (2013). EFFECT OF QUERCETIN ON UTERUS TISSUE HISTOLOGICAL CHANGES IN OVARIECTOMIZED RATS. JOURNAL OF CELL & TISSUE, 4(1), 77-83. SID. https://sid.ir/paper/188987/en

Vancouver: Copy

MOROVVATI H., NAJAFZADEH H., MENATIAN K.. EFFECT OF QUERCETIN ON UTERUS TISSUE HISTOLOGICAL CHANGES IN OVARIECTOMIZED RATS. JOURNAL OF CELL & TISSUE[Internet]. 2013;4(1):77-83. Available from: https://sid.ir/paper/188987/en

IEEE: Copy

H. MOROVVATI, H. NAJAFZADEH, and K. MENATIAN, “EFFECT OF QUERCETIN ON UTERUS TISSUE HISTOLOGICAL CHANGES IN OVARIECTOMIZED RATS,” JOURNAL OF CELL & TISSUE, vol. 4, no. 1, pp. 77–83, 2013, [Online]. Available: https://sid.ir/paper/188987/en

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