THE EFFECT OF MAGNETIC IRON OXIDE NANOPARTICLES ON EXPRESSION OF P53 PROTEIN IN TESTIS TISSUE OF BALB/C MICE BY IMMUNOHISTOCHEMICALLY STAINING

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KARIMI H.; HOJATI V.; SHIRAVI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF CELL & TISSUE Year:2017 | Volume:8 | Issue:2 Page(s): 120-126

Download Full-Text

Persian Verion

View:

709

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF MAGNETIC IRON OXIDE NANOPARTICLES ON EXPRESSION OF P53 PROTEIN IN TESTIS TISSUE OF BALB/C MICE BY IMMUNOHISTOCHEMICALLY STAINING

Author(s)

KARIMI H. | HOJATI V. | SHIRAVI A. | Issue Writer Certificate

Keywords

IRON OXIDE NANOPARTICLESQ1

INHALATIONQ2

P53 PROTEINQ1

TESTISQ2

IMMUNOHISTOCHEMISTRYQ2

Abstract

Aim: The purpose of this study was to investigate the effect of iron oxide magnetic nanoparticles on expression of P53 PROTEIN in TESTIS tissue of mouse.Material and methods: In this study, 18 male Balb/C mice were divided in three groups (six in each): The control group did not inhale nanoparticles and experimental 1 and 2 groups were treated with INHALATION exposure to IRON OXIDE NANOPARTICLES with concentration of 1000 and 2000<g/ml for 45 minutes daily, during 8 days. At the end of eight days, mice were dissected and testes were removed and tissue processing was performed. Changes in the expression of P53 PROTEIN were evaluated using immunohistochemically method (Avidin-Biotin staining) and cell counting.Results: Inhaled IRON OXIDE NANOPARTICLES by penetrating into the testicular tissue, increased the expression of P53 PROTEIN in experimental groups significantly (p<0.05).Conclusion: With the INHALATION of IRON OXIDE NANOPARTICLES at doses of 1000 and 2000 mg/ml, a significant increase in expression of P53 PROTEIN was observed in testicular tissue compared to the control group. By increasing the dose of nanoparticles, protein expression also increased.

Cites

No record.

References

No record.

Cite

APA: Copy

KARIMI, H., HOJATI, V., & SHIRAVI, A.. (2017). THE EFFECT OF MAGNETIC IRON OXIDE NANOPARTICLES ON EXPRESSION OF P53 PROTEIN IN TESTIS TISSUE OF BALB/C MICE BY IMMUNOHISTOCHEMICALLY STAINING. JOURNAL OF CELL & TISSUE, 8(2 ), 120-126. SID. https://sid.ir/paper/189016/en

Vancouver: Copy

KARIMI H., HOJATI V., SHIRAVI A.. THE EFFECT OF MAGNETIC IRON OXIDE NANOPARTICLES ON EXPRESSION OF P53 PROTEIN IN TESTIS TISSUE OF BALB/C MICE BY IMMUNOHISTOCHEMICALLY STAINING. JOURNAL OF CELL & TISSUE[Internet]. 2017;8(2 ):120-126. Available from: https://sid.ir/paper/189016/en

IEEE: Copy

H. KARIMI, V. HOJATI, and A. SHIRAVI, “THE EFFECT OF MAGNETIC IRON OXIDE NANOPARTICLES ON EXPRESSION OF P53 PROTEIN IN TESTIS TISSUE OF BALB/C MICE BY IMMUNOHISTOCHEMICALLY STAINING,” JOURNAL OF CELL & TISSUE, vol. 8, no. 2 , pp. 120–126, 2017, [Online]. Available: https://sid.ir/paper/189016/en

Related Journal Papers