INVESTIGATING THE EFFECTS OF RESVERATROL ON PROLIFERATION AND COLONY FORMATION OF DISSOCIATED HUMAN EMBRYONIC STEM CELLS

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SAFAEINEJAD Z.; NABIUNI M.; PEYMANI M.; GHAEDI K.; NASR ESFAHANI M.H.

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Journal: JOURNAL OF CELL & TISSUE Year:2018 | Volume:8 | Issue:4 Page(s): 322-331

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Title

INVESTIGATING THE EFFECTS OF RESVERATROL ON PROLIFERATION AND COLONY FORMATION OF DISSOCIATED HUMAN EMBRYONIC STEM CELLS

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Keywords

HUMAN EMBRYONIC STEM CELLSQ1

COLONY FORMATIONQ1

PROLIFERATIONQ1

RESVERATROLQ1

Abstract

Aim: The aim of this study was study the role of RESVERATROL (RSV) on PROLIFERATION and colony efficiency of dissociated HUMAN EMBRYONIC STEM CELLS (hESCs).Material and methods: In the current study, we used HESC line, RH6. Cells were cultured on the matrigelin supplemented hESC specific medium. Cell PROLIFERATION was estimated using cell counting and Brdu incorporation assays. The expression of colony efficiency markers (E-cadherin and b -catenin) was evaluated by western blot technique and b-catenin localization examined by immunecytochemistry staining.Results: We have shown that RSV promoted hPSCs PROLIFERATION without affecting their colony efficiency.Conclusion: According to these observations, RSVcan be suggested as a new supplement for hESCs culture.

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APA: Copy

SAFAEINEJAD, Z., NABIUNI, M., PEYMANI, M., GHAEDI, K., & NASR ESFAHANI, M.H.. (2018). INVESTIGATING THE EFFECTS OF RESVERATROL ON PROLIFERATION AND COLONY FORMATION OF DISSOCIATED HUMAN EMBRYONIC STEM CELLS. JOURNAL OF CELL & TISSUE, 8(4 ), 322-331. SID. https://sid.ir/paper/189036/en

Vancouver: Copy

SAFAEINEJAD Z., NABIUNI M., PEYMANI M., GHAEDI K., NASR ESFAHANI M.H.. INVESTIGATING THE EFFECTS OF RESVERATROL ON PROLIFERATION AND COLONY FORMATION OF DISSOCIATED HUMAN EMBRYONIC STEM CELLS. JOURNAL OF CELL & TISSUE[Internet]. 2018;8(4 ):322-331. Available from: https://sid.ir/paper/189036/en

IEEE: Copy

Z. SAFAEINEJAD, M. NABIUNI, M. PEYMANI, K. GHAEDI, and M.H. NASR ESFAHANI, “INVESTIGATING THE EFFECTS OF RESVERATROL ON PROLIFERATION AND COLONY FORMATION OF DISSOCIATED HUMAN EMBRYONIC STEM CELLS,” JOURNAL OF CELL & TISSUE, vol. 8, no. 4 , pp. 322–331, 2018, [Online]. Available: https://sid.ir/paper/189036/en

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