CIPROFLOXACIN LABELING BY TECHNETIUM99M AND ITS BIO DISTRIBUTION IN NORMAL AND INFECTED ANIMALS

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RAJABIFAR S.; POURIMANI R.; GHAFOURI M.; BOLOURI NOVIN F.; MORADKHANI S.; JALILIAN A.

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Journal: JOURNAL OF CELL & TISSUE Year:2011 | Volume:1 | Issue:2 Page(s): 29-35

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Title

CIPROFLOXACIN LABELING BY TECHNETIUM99M AND ITS BIO DISTRIBUTION IN NORMAL AND INFECTED ANIMALS

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Keywords

CIPROFLOXACINQ2

INFECTIONQ1

INFECTION DIAGNOSISQ3

TECHNETIUM99MQ3

Abstract

Aim: The aim of this study was to CIPROFLOXACIN labeling by technetium99m and its bio distribution in normal and infected laboratory animals for the site of INFECTION detection.Material and Methods: labeling of CIPROFLOXACIN by Tecnhetium99m at best concentration (2mg) and tin chloride at 50-600 micrograms concentration at different temperatures as well as pH using thin layer chromatography and different solvents were evaluated. Heart, lung, stomach, intestine, kidney, blood, spleen and muscle tissues separated and counted by HPGe.Results: Radiochemical purity found to be not less than 90% and serum stability was the same at least for 1hr bio distribution studies showed the muscle at 1 and 4 hrs. Were observed after injection.Conclusion: CIPROFLOXACIN labeling by direct method in high radiochemical purity may be used as a formulated compound for the site of INFECTION diagnosis in experimental animals.

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APA: Copy

RAJABIFAR, S., POURIMANI, R., GHAFOURI, M., BOLOURI NOVIN, F., MORADKHANI, S., & JALILIAN, A.. (2011). CIPROFLOXACIN LABELING BY TECHNETIUM^99M AND ITS BIO DISTRIBUTION IN NORMAL AND INFECTED ANIMALS. JOURNAL OF CELL & TISSUE, 1(2), 29-35. SID. https://sid.ir/paper/189043/en

Vancouver: Copy

RAJABIFAR S., POURIMANI R., GHAFOURI M., BOLOURI NOVIN F., MORADKHANI S., JALILIAN A.. CIPROFLOXACIN LABELING BY TECHNETIUM^99M AND ITS BIO DISTRIBUTION IN NORMAL AND INFECTED ANIMALS. JOURNAL OF CELL & TISSUE[Internet]. 2011;1(2):29-35. Available from: https://sid.ir/paper/189043/en

IEEE: Copy

S. RAJABIFAR, R. POURIMANI, M. GHAFOURI, F. BOLOURI NOVIN, S. MORADKHANI, and A. JALILIAN, “CIPROFLOXACIN LABELING BY TECHNETIUM^99M AND ITS BIO DISTRIBUTION IN NORMAL AND INFECTED ANIMALS,” JOURNAL OF CELL & TISSUE, vol. 1, no. 2, pp. 29–35, 2011, [Online]. Available: https://sid.ir/paper/189043/en

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