COMPARISON OF SPERM PARAMETERS AND DNA INTEGRITY BETWEEN FERTILE AND VARICOCELE INDIVIDUALS

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ABASI H.; ELAHE NAVAEIAN KALAT E.; TAVALAEE M.; NASR ESFAHANI M.H.

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Journal: JOURNAL OF CELL & TISSUE Year:2012 | Volume:3 | Issue:2 Page(s): 171-177

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Title

COMPARISON OF SPERM PARAMETERS AND DNA INTEGRITY BETWEEN FERTILE AND VARICOCELE INDIVIDUALS

Author(s)

ABASI H. | ELAHE NAVAEIAN KALAT E. | TAVALAEE M. | NASR ESFAHANI M.H. | Issue Writer Certificate

Keywords

DNA DAMAGEQ2

SEMEN PARAMETERSQ2

VARICOCELEQ2

Abstract

Aim: VARICOCELE is the most common causes of male sterility that is caused progressive testicular damage over time. In this study sperm parameters and their DNA integrity was compared in VARICOCELE and fertile people.Material and Methods: The study performed on 55 grades II and III VARICOCELE people and 25 fertiles. SEMEN PARAMETERS (sperm count, motility and morphology) and sperm DNA health were assessed using TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling). Data were analyzed by SPSS software.Result: VARICOCELEs SEMEN PARAMETERS consist of sperm count, motility and morphology had significantly low quality in comparison with fertile people. Also damaged DNA sperms percentage of VARICOCELE people (14.34%±1.43) was significantly increased compared to fertile people (9.2%±1.36). Sperm parameters and DNA DAMAGE percentage correlation showed that there is a reversed correlation between DNA DAMAGE percentage and sperm density and significant and positive correlations with sperm abnormal morphology.Conclusion: Testicular temperature increasing in VARICOCELE people, caused to low quality of sperm parameters and also high sperm DNA DAMAGEs. Therefore, VARICOCELE people are confronted with spermatogenesis process deficiency.

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APA: Copy

ABASI, H., ELAHE NAVAEIAN KALAT, E., TAVALAEE, M., & NASR ESFAHANI, M.H.. (2012). COMPARISON OF SPERM PARAMETERS AND DNA INTEGRITY BETWEEN FERTILE AND VARICOCELE INDIVIDUALS. JOURNAL OF CELL & TISSUE, 3(2), 171-177. SID. https://sid.ir/paper/189061/en

Vancouver: Copy

ABASI H., ELAHE NAVAEIAN KALAT E., TAVALAEE M., NASR ESFAHANI M.H.. COMPARISON OF SPERM PARAMETERS AND DNA INTEGRITY BETWEEN FERTILE AND VARICOCELE INDIVIDUALS. JOURNAL OF CELL & TISSUE[Internet]. 2012;3(2):171-177. Available from: https://sid.ir/paper/189061/en

IEEE: Copy

H. ABASI, E. ELAHE NAVAEIAN KALAT, M. TAVALAEE, and M.H. NASR ESFAHANI, “COMPARISON OF SPERM PARAMETERS AND DNA INTEGRITY BETWEEN FERTILE AND VARICOCELE INDIVIDUALS,” JOURNAL OF CELL & TISSUE, vol. 3, no. 2, pp. 171–177, 2012, [Online]. Available: https://sid.ir/paper/189061/en

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