SIMULATION OF THE PRODUCTION PROCESS OF ASPERGILLUS NIGER SINGLE CELL PROTEIN BASE ON UN-STRUCTURED KINETIC MODELS

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ARDESTANI FATEMEH; KASEBKAR ROXANA

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Journal: JOURNAL OF MICROBIAL WORLD Year:2016 | Volume:8 | Issue:4 (25) Page(s): 308-319

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Title

SIMULATION OF THE PRODUCTION PROCESS OF ASPERGILLUS NIGER SINGLE CELL PROTEIN BASE ON UN-STRUCTURED KINETIC MODELS

Author(s)

ARDESTANI FATEMEH | KASEBKAR ROXANA | Issue Writer Certificate

Keywords

ASPERGILLUS NIGERQ1

SINGLE CELL PROTEINQ2

UN-STRUCTURED MODELSQ2

Abstract

Background & Objectives: Design of the production of SINGLE CELL PROTEINs depends on definition of the growth template of the producer microorganisms. This study was aimed to evaluate the production of ASPERGILLUS NIGER SINGLE CELL PROTEIN and simulation of cell biomass production based on several UN-STRUCTURED MODELS.Materials & Methods: In this experimental study, the fermentative process of SINGLE CELL PROTEIN production was conducted in batch submerged culture with optimum culture medium formulation at 250C, pH 6 and 300 rpm for 200 h in an incubator shaker. At the end of process, the content of shaker flasks was used to analysis glucose concentration, cell dry weight and protein content in cell biomass.Results: The result simulation by Monod, Moser and Logistic models showed 92% 63% and 83% similarity, respectively. Increase in the pH from 3.5 to 6 caused 71% enhancement in protein content in cell biomass. However, pH more than 6 led to decrease in the cell biomass protein content and this values reached to 29% a pH 7. Increases in the initial glucose concentration from 10 to 50 g. L-1 did not show considerable effects on the cell biomass protein content. Cell biomass protein content of the media containing 50 g. L-1 initial glucose was only 5.67% more than the medium contained of 10 g. L-1 initial glucose.Conclusion: The Monod kinetic model was proposed as a suitable model to simulate A. niger behaviour. Furthermore, pH of the media affects cell biomass protein content. However, initial glucose concentration in the media did not show significant effects on the cell biomass protein content.

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APA: Copy

ARDESTANI, FATEMEH, & KASEBKAR, ROXANA. (2016). SIMULATION OF THE PRODUCTION PROCESS OF ASPERGILLUS NIGER SINGLE CELL PROTEIN BASE ON UN-STRUCTURED KINETIC MODELS. JOURNAL OF MICROBIAL WORLD, 8(4 (25)), 308-319. SID. https://sid.ir/paper/189331/en

Vancouver: Copy

ARDESTANI FATEMEH, KASEBKAR ROXANA. SIMULATION OF THE PRODUCTION PROCESS OF ASPERGILLUS NIGER SINGLE CELL PROTEIN BASE ON UN-STRUCTURED KINETIC MODELS. JOURNAL OF MICROBIAL WORLD[Internet]. 2016;8(4 (25)):308-319. Available from: https://sid.ir/paper/189331/en

IEEE: Copy

FATEMEH ARDESTANI, and ROXANA KASEBKAR, “SIMULATION OF THE PRODUCTION PROCESS OF ASPERGILLUS NIGER SINGLE CELL PROTEIN BASE ON UN-STRUCTURED KINETIC MODELS,” JOURNAL OF MICROBIAL WORLD, vol. 8, no. 4 (25), pp. 308–319, 2016, [Online]. Available: https://sid.ir/paper/189331/en

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