EVALUATION OF THE PROTECTIVE EFFECT OF NIGELLA SATIVA OIL ON OVARIAN FOLLICLES IN MICE TREATED WITH SILVER NANOPARTICLES

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SHARIATZADEH S.M.A.; KHAJAVI JAFARABAD MOZHGAN

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Journal: JOURNAL OF DEVELOPMENTAL BIOLOGY Year:2018 | Volume:10 | Issue:1 Page(s): 11-19

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Title

EVALUATION OF THE PROTECTIVE EFFECT OF NIGELLA SATIVA OIL ON OVARIAN FOLLICLES IN MICE TREATED WITH SILVER NANOPARTICLES

Author(s)

SHARIATZADEH S.M.A. | KHAJAVI JAFARABAD MOZHGAN | Issue Writer Certificate

Keywords

SILVER NANOPARTICLESQ2

OVARIAN FOLLICLESQ2

NIGELLA SATIVA OILQ1

MICEQ2

Abstract

Aim: the effect of NIGELLA SATIVA OIL (NSO) as an efficient antioxidant on OVARIAN FOLLICLES following treatment with SILVER NANOPARTICLES (SNP) in adult MICE.Material and methods: Twenty-four adult NMRI MICE, weighing 27-30g were used in the present experiment. The animals were kept under optimum conditions of temperature (At 21 ± 2oC and ambient lighting conditions 12 hours of darkness and 12 hours of light) humidity and maintained on standard pellet diet with adequate water. They were divided into four groups of (six MICE per group): control; SILVER NANOPARTICLES (300 mg/kg/day, orally), NIGELLA SATIVA OIL (5 ml/kg/day, orally) and finally SILVER NANOPARTICLES plus NIGELLA SATIVA OIL. After 30 days, the MICE were sacrificed and the ovary tissues were separated. The results were analyzed using one-way ANOVA and Tukey’s test, and the means were signiﬁcantly different at P<0.05.Results: The results of this study showed that, the mean total volume of ovary and the number of primordial, primary, secondary and graph follicles significantly decreased in the SILVER NANOPARTICLES group compared with the control group (p<0.05). NIGELLA SATIVA OIL significantly increased the above parameters in the SNP+NSO group compared to SILVER NANOPARTICLES group (p<0.05). Furthermore, the number of follicles and total volume of ovary significantly increased in the NIGELLA SATIVA OIL treated MICE compared to the control ones (p<0.05) (Table 1).Conclusion: So it is not far-fetched that this oil has improved the factors in our study.

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APA: Copy

SHARIATZADEH, S.M.A., & KHAJAVI JAFARABAD, MOZHGAN. (2018). EVALUATION OF THE PROTECTIVE EFFECT OF NIGELLA SATIVA OIL ON OVARIAN FOLLICLES IN MICE TREATED WITH SILVER NANOPARTICLES. JOURNAL OF DEVELOPMENTAL BIOLOGY, 10(1 ), 11-19. SID. https://sid.ir/paper/193130/en

Vancouver: Copy

SHARIATZADEH S.M.A., KHAJAVI JAFARABAD MOZHGAN. EVALUATION OF THE PROTECTIVE EFFECT OF NIGELLA SATIVA OIL ON OVARIAN FOLLICLES IN MICE TREATED WITH SILVER NANOPARTICLES. JOURNAL OF DEVELOPMENTAL BIOLOGY[Internet]. 2018;10(1 ):11-19. Available from: https://sid.ir/paper/193130/en

IEEE: Copy

S.M.A. SHARIATZADEH, and MOZHGAN KHAJAVI JAFARABAD, “EVALUATION OF THE PROTECTIVE EFFECT OF NIGELLA SATIVA OIL ON OVARIAN FOLLICLES IN MICE TREATED WITH SILVER NANOPARTICLES,” JOURNAL OF DEVELOPMENTAL BIOLOGY, vol. 10, no. 1 , pp. 11–19, 2018, [Online]. Available: https://sid.ir/paper/193130/en

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