POLYMORPHISM OF BOLA-BRB 3.2 GENE IN IRANIAN HOLSTEIN BY USE OF PCR-RFLP METHOD

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NIKBAKHT BOROUJENI GH.R.; EMAM S.M.

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Journal: Year:2008 | Volume:20 | Issue:4 (77 IN ANIMAL AND FISHERIES SCIENCES) Page(s): 141-148

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Title

POLYMORPHISM OF BOLA-BRB 3.2 GENE IN IRANIAN HOLSTEIN BY USE OF PCR-RFLP METHOD

Author(s)

NIKBAKHT BOROUJENI GH.R. | EMAM S.M. | Issue Writer Certificate

Keywords

IRANIAN HOLSTEINQ3

MHCQ3

BOLA-DRB3Q3

PCR-RFLPQ3

Abstract

Enhancing disease resistance in animal production can be achieved by genetic improvement programs. The best-characterized genetic control of disease resistance and immune response in animals is that associated with the MHC. Respond to specific antigens is closely related to MHC genes and their associations might therefore provide precious answers to main questions about the host pathogen interactions. In cattle there is an association between possession of certain BOLA-DRB3 locus (MHC class II) and resistance or susceptibility to infectious diseases. Polymorphism of exon 2 of the BOLA-DRB3 gene was investigated by the PCR-RFLP method in 55 IRANIAN HOLSTEIN cattle. In this study, 26 different alleles were recognized. Among those identified are known alleles as well as 2 previously unrecognized alleles. As a second goal, allelic frequencies were determined in a total sample. Frequencies of alleles mediating resistance and susceptibility to leukemia, FMD and mastitis were revealed. High frequency of the alleles related to FMD and EBL in Iranian cattle and low level of mastitis susceptible alleles could be due to special point of view in breeding programs neglecting resistance to diseases that have no obvious economic burden.

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APA: Copy

NIKBAKHT BOROUJENI, GH.R., & EMAM, S.M.. (2008). POLYMORPHISM OF BOLA-BRB 3.2 GENE IN IRANIAN HOLSTEIN BY USE OF PCR-RFLP METHOD. PAJOUHESH-VA-SAZANDEGI, 20(4 (77 IN ANIMAL AND FISHERIES SCIENCES)), 141-148. SID. https://sid.ir/paper/20173/en

Vancouver: Copy

NIKBAKHT BOROUJENI GH.R., EMAM S.M.. POLYMORPHISM OF BOLA-BRB 3.2 GENE IN IRANIAN HOLSTEIN BY USE OF PCR-RFLP METHOD. PAJOUHESH-VA-SAZANDEGI[Internet]. 2008;20(4 (77 IN ANIMAL AND FISHERIES SCIENCES)):141-148. Available from: https://sid.ir/paper/20173/en

IEEE: Copy

GH.R. NIKBAKHT BOROUJENI, and S.M. EMAM, “POLYMORPHISM OF BOLA-BRB 3.2 GENE IN IRANIAN HOLSTEIN BY USE OF PCR-RFLP METHOD,” PAJOUHESH-VA-SAZANDEGI, vol. 20, no. 4 (77 IN ANIMAL AND FISHERIES SCIENCES), pp. 141–148, 2008, [Online]. Available: https://sid.ir/paper/20173/en

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