THE TERATOGENIC EFFECTS OF BROMADIOLONE ON RAT FETUS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HEYDARI NASRABADI M.; HAGHIGHI F.; SARAFRAZI ESFANDABADI F.; JAHANBAKHSH L.; RAHIMI MOTLAGH M.; ZAHEDI F.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL Year:2012 | Volume:2 | Issue:5 Page(s): 53-58

Download Full-Text

Persian Verion

View:

922

Download:

Cites:

Information Journal Paper

Title

THE TERATOGENIC EFFECTS OF BROMADIOLONE ON RAT FETUS

Author(s)

Keywords

BROMADIOLONEQ2

TERATOGENIC EFFECTSQ2

RAT FETUSQ2

Abstract

Aim and background: BROMADIOLONE is one of the well known toxic substances. Toxic effects of BROMADIOLONE have been studied more on different organs of experimental animals. But studying the effects of the toxin on fetus and placenta is still insufficient. In this study, we studied rat embryos exposed to BROMADIOLONE in a short period.Materials and Methods: Animals used in this study were Wistar rats. After the occurrence of pregnancy, female rats were placed in two groups, randomly (n=7). BROMADIOLONE was given to the experimental group animals on the day 5 of pregnancy in one turn in a dose of 0.11 mg/kg and then sterilized water was given to the control group. On the 15th day of pregnancy, rats were killed and embryos were taken out of the womb. Weight and diameter of embryos were measured and then embryos were used for histological and statistical studies.Results: In the experimental group, there was no significant difference between fetal weight and size of experimented and control groups but in experimental group there were significant decreased in the number of embryos due to fetal atrophy (p<0.05). Hemorrhagic areas of the external structure in the experimental embryos and although, edema of gastric, intestinal lobe and liver was also seen.Conclusion: These results showed that BROMADIOLONE causes teratogenic malformation in the ratfetus.

Cites

No record.

References

No record.

Cite

APA: Copy

HEYDARI NASRABADI, M., HAGHIGHI, F., SARAFRAZI ESFANDABADI, F., JAHANBAKHSH, L., RAHIMI MOTLAGH, M., & ZAHEDI, F.. (2012). THE TERATOGENIC EFFECTS OF BROMADIOLONE ON RAT FETUS. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 2(5), 53-58. SID. https://sid.ir/paper/204409/en

Vancouver: Copy

HEYDARI NASRABADI M., HAGHIGHI F., SARAFRAZI ESFANDABADI F., JAHANBAKHSH L., RAHIMI MOTLAGH M., ZAHEDI F.. THE TERATOGENIC EFFECTS OF BROMADIOLONE ON RAT FETUS. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2012;2(5):53-58. Available from: https://sid.ir/paper/204409/en

IEEE: Copy

M. HEYDARI NASRABADI, F. HAGHIGHI, F. SARAFRAZI ESFANDABADI, L. JAHANBAKHSH, M. RAHIMI MOTLAGH, and F. ZAHEDI, “THE TERATOGENIC EFFECTS OF BROMADIOLONE ON RAT FETUS,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 2, no. 5, pp. 53–58, 2012, [Online]. Available: https://sid.ir/paper/204409/en

Related Journal Papers