EVALUATION OF ANTI TUMOR PROPERTIES OF INDOLOQUINAZOLINE ON MCF-7 CELL LINE

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BIKHOF TORBATI MARYAM; SHAABANZADEH MASOUD; AZADIAN SOMAYEH

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Paper Information

Journal: NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL Year:2016 | Volume:6 | Issue:21 Page(s): 117-121

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Title

EVALUATION OF ANTI TUMOR PROPERTIES OF INDOLOQUINAZOLINE ON MCF-7 CELL LINE

Author(s)

BIKHOF TORBATI MARYAM | SHAABANZADEH MASOUD | AZADIAN SOMAYEH | Issue Writer Certificate

Keywords

INDOLOQUINAZOLINEQ2

CISPLATINQ2

ANTITUMORQ2

MCF-7 CELL LINEQ2

Abstract

Aim and Background: Chemotherapy is a category of cancer treatment that uses chemical agents. The harmfulness of chemotherapy on normal cells by killing cells is the most common side-effects of chemotherapy. Characterization and selection of new powerful chemotherapy agents which have low side effects are important. INDOLOQUINAZOLINE has a variety of biological activities such as antimicrobial activities and cytotoxic properties. In this study, cytotoxic effect of synthetic INDOLOQUINAZOLINE compound was studied on breast cancer cell line and compared with CISPLATIN.Materials and Methods: Anti tumor activity of INDOLOQUINAZOLINE compound and CISPLATIN was studied on breast cancer cell line, MCF-7, by MTT assay.Results: INDOLOQUINAZOLINE compound showed ANTITUMOR activity with IC50 of 6.83 mg/ml by being Compared with 39.13 mg/ml of CISPLATIN, as a kind of standard drug on MCF-7 CELL LINE.Conclusion: The results showed INDOLOQUINAZOLINE is cytotoxic more than CISPLATIN on MCF-7 CELL LINE.

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APA: Copy

BIKHOF TORBATI, MARYAM, SHAABANZADEH, MASOUD, & AZADIAN, SOMAYEH. (2016). EVALUATION OF ANTI TUMOR PROPERTIES OF INDOLOQUINAZOLINE ON MCF-7 CELL LINE. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 6(21), 117-121. SID. https://sid.ir/paper/204436/en

Vancouver: Copy

BIKHOF TORBATI MARYAM, SHAABANZADEH MASOUD, AZADIAN SOMAYEH. EVALUATION OF ANTI TUMOR PROPERTIES OF INDOLOQUINAZOLINE ON MCF-7 CELL LINE. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2016;6(21):117-121. Available from: https://sid.ir/paper/204436/en

IEEE: Copy

MARYAM BIKHOF TORBATI, MASOUD SHAABANZADEH, and SOMAYEH AZADIAN, “EVALUATION OF ANTI TUMOR PROPERTIES OF INDOLOQUINAZOLINE ON MCF-7 CELL LINE,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 6, no. 21, pp. 117–121, 2016, [Online]. Available: https://sid.ir/paper/204436/en

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