CYTOTOXICITY OF NISIN ON HUMAN GASTRIC CARCINOMA (AGS) CELL LINE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GOODARZI FARIBA; ASADI ASADOLLAH; ZAHRI SABER

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL Year:2013 | Volume:3 | Issue:10 Page(s): 9-13

Download Full-Text

Persian Verion

View:

1,396

Download:

Cites:

Information Journal Paper

Title

CYTOTOXICITY OF NISIN ON HUMAN GASTRIC CARCINOMA (AGS) CELL LINE

Author(s)

GOODARZI FARIBA | ASADI ASADOLLAH | ZAHRI SABER | Issue Writer Certificate

Keywords

NISINQ2

AGSQ1

CYTOTOXICITYQ2

Abstract

Introduction and purpose: Gastrointestinal cancers are among the most frequently occurring cancers worldwide. Environmental and inherited factors could be contributed to the etiology of these cancers. Lifestyle factors such as dietary habits, physical activity and smoking may play an important role in the occurrence of these types of cancer. Gastric cancer is the fourth most common cancer and second leading cause of cancer death worldwide. NISIN is an antimicrobial peptide with 34 amino acids and due to having the Lantionin amino acid categorized as Lantibiotic peptides family. The purpose of this study is to evaluate the NISIN effect on cell CYTOTOXICITY of gastric cancer.Method: For evaluation of NISIN cytotoxic effect on AGS cell line; they were cultured in 96-well plates at a density of 1×104 cells per well and incubated for overnight 37oC. After 24 h, cells were treated in a triplicate manner with different concentrations of NISIN including 0, 10, 20, 40, 60 and 80 micromolar and for each concentration was repeated 3 times. The cytotoxic effect of NISIN on cells in the intervals 24, 48 and 72 h after treatment were investigated.Results: In each interval with concentration increase, cells viability reduction was observed, In addition, CYTOTOXICITY increased in longer time treatment.Discussion: Many peptides having biological activities are used as therapeutic agents. These peptides, including NISIN, which causes death in AGS cells, CYTOTOXICITY effect of NISIN on cells is concentration and time depended.

Cites

No record.

References

No record.

Cite

APA: Copy

GOODARZI, FARIBA, ASADI, ASADOLLAH, & ZAHRI, SABER. (2013). CYTOTOXICITY OF NISIN ON HUMAN GASTRIC CARCINOMA (AGS) CELL LINE. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 3(10), 9-13. SID. https://sid.ir/paper/204468/en

Vancouver: Copy

GOODARZI FARIBA, ASADI ASADOLLAH, ZAHRI SABER. CYTOTOXICITY OF NISIN ON HUMAN GASTRIC CARCINOMA (AGS) CELL LINE. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2013;3(10):9-13. Available from: https://sid.ir/paper/204468/en

IEEE: Copy

FARIBA GOODARZI, ASADOLLAH ASADI, and SABER ZAHRI, “CYTOTOXICITY OF NISIN ON HUMAN GASTRIC CARCINOMA (AGS) CELL LINE,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 3, no. 10, pp. 9–13, 2013, [Online]. Available: https://sid.ir/paper/204468/en

Related Journal Papers