EVALUATION THE EFFECT OF NANONIOSOMAL CISPLATIN ON BRAIN CANCER CELL LINE C6

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

BABAEI MAHROKH; AKBARZADEH AZIM; ARDJMAND MEHDI; SEIFKORDI ALIAKBAR

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL Year:2016 | Volume:6 | Issue:23 Page(s): 61-75

Download Full-Text

Persian Verion

View:

994

Download:

Cites:

Information Journal Paper

Title

EVALUATION THE EFFECT OF NANONIOSOMAL CISPLATIN ON BRAIN CANCER CELL LINE C6

Author(s)

BABAEI MAHROKH | AKBARZADEH AZIM | ARDJMAND MEHDI | SEIFKORDI ALIAKBAR | Issue Writer Certificate

Keywords

DRUG DELIVERYQ2

CISPLATINQ2

NIOSOMEQ1

MTTQ1

C6Q1

Abstract

Aim and Background: Nowadays, applying nanocarriers has increased dramatically in DRUG DELIVERY systems. NIOSOME is one of the nanocarriers with non-ionic surfactant which increases the stability of drug in the body. Since using CISPLATIN in treatment of cancer has some side effects, CISPLATIN was nanoniosomed. Material and methods: To prepare NIOSOME, span 60 and cholesterol were used. Mean diameter of particles was determined by Zeta sizer. Encapsulation efficiency and drug release were measured by spectrophotometry method. Cytotoxicity effect of the formulation on C6 cell line was studied by MTT assay.Results: Mean diameter of particles was verified in scale of nano. Encapsulation efficiency and released in 48 hours were be 43.6% and 97%, respectively. The cytotoxicity effect of nanoniosomal CISPLATIN was 38.6 mg/ml.Conclusion: The present study showed that to reduce side effects of CISPLATIN and increase its toxicity, we can use nanoniosomal formulation.

Cites

No record.

References

No record.

Cite

APA: Copy

BABAEI, MAHROKH, AKBARZADEH, AZIM, ARDJMAND, MEHDI, & SEIFKORDI, ALIAKBAR. (2016). EVALUATION THE EFFECT OF NANONIOSOMAL CISPLATIN ON BRAIN CANCER CELL LINE C6. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, 6(23), 61-75. SID. https://sid.ir/paper/204733/en

Vancouver: Copy

BABAEI MAHROKH, AKBARZADEH AZIM, ARDJMAND MEHDI, SEIFKORDI ALIAKBAR. EVALUATION THE EFFECT OF NANONIOSOMAL CISPLATIN ON BRAIN CANCER CELL LINE C6. NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL[Internet]. 2016;6(23):61-75. Available from: https://sid.ir/paper/204733/en

IEEE: Copy

MAHROKH BABAEI, AZIM AKBARZADEH, MEHDI ARDJMAND, and ALIAKBAR SEIFKORDI, “EVALUATION THE EFFECT OF NANONIOSOMAL CISPLATIN ON BRAIN CANCER CELL LINE C6,” NEW CELLULAR & MOLECULAR BIOTECHNOLOGY JOURNAL, vol. 6, no. 23, pp. 61–75, 2016, [Online]. Available: https://sid.ir/paper/204733/en

Related Journal Papers